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Cochlear synaptopathy: new findings in animal and human research
(Walter de Gruyter GMBH, 2020)
In animal models, prolonged exposure (2 h) to high-level noise causes an irreparable damage to the synapses between the inner hair cells and auditory nerve fibers within the cochlea. Nevertheless, this injury does not ...
The ongoing search for cochlear synaptopathy in humans: Masked thresholds for brief tones in Threshold Equalizing Noise
(Elsevier, 2020)
his study aimed to advance towards a clinical diagnostic method for detection of cochlear synaptopathy with the hypothesis that synaptopathy should be manifested in elevated masked thresholds for brief tones. This hypothesis ...
Synaptoprotection in Perinatal Asphyxia: An Experimental Approach
(Frontiers Media S.A., 2020-09-23)
Perinatal asphyxia (PA) is an obstetric complication occurring when the oxygen supply to the newborn is temporally interrupted. This health problem is associated with high morbimortality in term and preterm neonates. It ...
Amyloid Precursor Protein in Central and Peripheral Cholinergic Synaptopathies
(Nova Science Publishers, 2011-05)
Alzheimer´s disease is the most widespread form of dementia in the elderly. One of the characteristics of this disease is the profound functional deficit of the cholinergic system as a consequence of synaptic loss. Amyloid ...
Could Perinatal Asphyxia Induce a Synaptopathy? New Highlights from an Experimental Model
(Hindawi Limited, 2017)
Synaptoprotection in Perinatal Asphyxia: An Experimental Approach
(Frontiers Media, 2020-09)
Perinatal asphyxia (PA) is an obstetric complication occurring when the oxygen supply to the newborn is temporally interrupted. This health problem is associated with high morbimortality in term and preterm neonates. It ...
Preventing presbycusis in mice with enhanced medial olivocochlear feedback
(National Academy of Sciences, 2020)
"Growing old" is the most common cause of hearing loss. Age-related hearing loss (ARHL) (presbycusis) first affects the ability to understand speech in background noise, even when auditory thresholds in quiet are normal. ...
Reduced suprathreshold auditory nerve responses are associated with slower processing speed and thinner temporal and parietal cortex in presbycusis
(Public Library Science, 2020)
Epidemiological evidence shows an association between hearing loss and dementia in elderly people. However, the mechanisms that connect hearing impairments and cognitive decline are still unknown. Here we propose that a ...
Subclinical hearing loss associated with aging
(Elsevier, 2023)
Objective
Contribute to clarifying the existence of subclinical hearing deficits associated with aging.