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Structural bioinformatics study of cyclin-dependent kinases complexed with inhibitors
(Editora Unesp, 2003-01-01)
O presente trabalho descreve modelos moleculares para os complexos binários CDK9, CDK5 e CDK1 complexados com Flavopiridol e Roscovitina. Esses modelos estruturais indicam que os inibidores ligam-se fortemente ao sítio de ...
Structural bioinformatics study of cyclin-dependent kinases complexed with inhibitors
(Editora Unesp, 2003-01-01)
O presente trabalho descreve modelos moleculares para os complexos binários CDK9, CDK5 e CDK1 complexados com Flavopiridol e Roscovitina. Esses modelos estruturais indicam que os inibidores ligam-se fortemente ao sítio de ...
Bioinformatic prediction of polymerase elements in the rotavirus VP1 protein
(Sociedad de Biología de Chile, 2006)
Structural bioinformatics study of PNP from Schistosoma mansoni
(Elsevier B.V., 2004-09-10)
The parasite Schistosoma mansoni lacks the de novo pathway for purine biosynthesis and depends on salvage pathways for its purine requirements. Schistosomiasis is endemic in 76 countries and territories and amongst the ...
Structural bioinformatics study of PNP from Schistosoma mansoni
(Elsevier B.V., 2004-09-10)
The parasite Schistosoma mansoni lacks the de novo pathway for purine biosynthesis and depends on salvage pathways for its purine requirements. Schistosomiasis is endemic in 76 countries and territories and amongst the ...
Structural bioinformatics study of PNP from Schistosoma mansoni
(Elsevier B.V., 2014)
Predicting peptides structure with solvation potential and rotamer library dependent of the backbone
(Elsevier B.V., 2008-05-15)
In this work, genetic algorithms concepts along with a rotamer library dependent of backbone and implicit solvation potential are used to study the tertiary structure of peptides. We starting from known primary sequence ...
Predicting peptides structure with solvation potential and rotamer library dependent of the backbone
(Elsevier B.V., 2008-05-15)
In this work, genetic algorithms concepts along with a rotamer library dependent of backbone and implicit solvation potential are used to study the tertiary structure of peptides. We starting from known primary sequence ...
Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
(Elsevier B.V., 2002-10-11)
Here is described a structural model for the binary complex CDK5-roscovitine. Roscovitine has been shown to potently inhibit cyclin-dependent kinases 1, 2 and 5 (CDK1, 2, and 5), and the structure of CDK2 complexed with ...
Structural bioinformatics study of EPSP synthase from Mycobacterium tuberculosis
(Elsevier B.V., 2003-12-19)
The shikimate pathway is an attractive target for herbicides and antimicrobial agent development because it is essential in algae, higher plants, bacteria, and fungi, but absent from mammals. Homologues to enzymes in the ...