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Novel role for histamine through classical h1 and h2 receptors: regulation of leydig cell steroidogenesis and its implications for male reproductive function
(Springer, 2010)
Most of the physiological functions of HA described to date have been linked to the well-characterized H1 and H2 receptors. Nevertheless, extensive research is continuously going on to elucidate new roles for these receptors. ...
Growth factors and steroidogenesis in the bovine placenta
(Belo Horizonte, 2008)
The control of placental hormone biosynthesis is critical during gestation, since their coordinated action is essential for the normal progress of pregnancy. Hormonal synthesis regulation in placenta is still not elucidated ...
Regulation of human luteal steroidogenesis in vitro by nitric oxide
(1998)
To evaluate the effect of nitric oxide (NO·) in human
corpus luteum (CL) function, we investigated the
expression and the presence of NO· synthase (NOS) in
the human CL and the action of NO· on the in vitro
luteal ...
Multigenerational Effects of an Environmentally Relevant Phthalate Mixture on Reproductive Parameters and Ovarian miRNA Expression in Female Rats
(Oxford Univ Press, 2022-06-28)
Phthalates are endocrine-disrupting chemicals used in many consumer products. Our laboratory previously developed an environmentally relevant phthalate mixture consisting of 6 phthalates and found that it disrupted female ...
Histamine inhibits adrenocortical cell proliferation but does not affect steroidogenesis.
(Bioscientifica, 2014-03-07)
Histamine (HA) is a neurotransmitter synthesized in most mammalian tissues exclusively by histidine decarboxylase enzyme. Among the plethora of actions mediated by HA, the modulatory effects on steroidogenesis and proliferation ...
Dual role of histamine in modulation of Leydig cell steroidogenesis via HRH1 and HRH2 receptor subtypes
(Society for the Study of Reproduction, 2005-11-01)
Although several reports indicate effects of histamine (HA) on female reproductive functions, scant literature exists to suggest a physiological role of HA in the male gonad. In the present study, we report a dual ...
Oxidative stress and altered steroidogenesis in the ovary by cholinergic stimulation of coeliac ganglion in the first proestrous in rats. Implication of nitric oxide
(Academic Press Inc Elsevier Science, 2016-02-29)
An ex-vivo Coeliac Ganglion-Superior Ovarian Nerve-Ovary (CG-SON-O) system from virgin rats in the first proestrous was used to test whether cholinergic stimulation of CG affects oxidative status and steroidogenesis in the ...
Effects of heme oxygenase isozymes on Leydig cells steroidogenesis
(BioScientifica, 2009-10)
In the present study, we demonstrate the expression of heme oxygenase (HO) isozymes, HO-1 and HO-2 (listed as HMOX1 and HMOX2 in the MGI Database), in MA-10 Leydig tumor cells and its effect on steroidogenesis. The well-known ...
Effects of in vitro exposure to butylparaben and di-(2 ethylhexyl) phthalate, alone or in combination, on ovarian function
(2016-09-01)
Parabens and phthalates are commercial chemicals widely used in the manufacture of industrial and consumer products frequently found as contaminants in biological fluids. We evaluated the effects of di-(2-ethylhexyl) ...