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Stavudine effects on rat pregnancy outcome

Barreto, RLB; Simoes, M. D.; Amed, A. M.; Soares, J. M.; Oliveira, R. M.; Kulay, L. (Blackwell Publishing Asia, 2004-06-01)

Objective: Stavudine is an inhibitor of HIV reverse transcriptase and acts as a chain terminator during DNA synthesis. the aim of the study presented here was to evaluate the effects of stavudine during rat pregnancy.Methods: ...

Effects of chronic stavudine exposure on liver, pancreas and kidneys of pregnant rats and their fetuses: Morphological and biochemical aspects

Barreto, Regina Lucia Braga; Soares, Jose Maria; Simoes, Ricardo Santos; Maciel, Gustavo Arantes Rosa; Jesus Simoes, Manuel de; Kulay, Luiz (Elsevier B.V., 2006-09-01)

Objective: To study the morphological and biochemical effects on liver, pancreas and kidney of pregnant rats and their fetuses subjected to stavudine treatment.Methods: Forty animals were distributed in four groups E1, E2, ...

Effects of daily intake of zidovudine-stavudine on rat pregnancy outcome: biological essay

Restum Antonio, E.; Pereira Fontes, T. M.; SIMÕES, Ricardo dos Santos; Moreira de Carvalho, A.; Espiridiao, S.; Uchiyama Nakamura, M.; Kulay, L., Jr. (I R O G CANADA, INCMONTREAL, 2012)

Purpose: To evaluate the effects at term of a highly active antiretroviral drug association when administered for the whole period of rat pregnancy. Methods: Forty pregnant rats weighing about 200 g were randomly divided ...

Effects of daily intake of zidovudine-stavudine on rat pregnancy outcome: biological essay

Antonio, Eliana Maria Restum [UNIFESP]; Fontes, Tereza Maria Pereira [UNIFESP]; Simoes, Ricardo Santos [UNIFESP]; Carvalho, Adelino Moreira de [UNIFESP]; Espiridião, Silvia [UNIFESP]; Nakamura, Mary Uchiyama [UNIFESP]; Kulay Júnior, Luiz [UNIFESP] (I R O G Canada, Inc, 2012-01-01)

Biowaiver monographs for immediate-release solid oral dosage forms: Stavudine

Silva, Arthur L. L.; Cristofoletti, Rodrigo; Storpirtis, Silvia; Sousa, Varley D.; Junginger, Hans E.; Shah, Vinod P.; Stavchansky, Salomon; Dressman, Jennifer B.; Barends, Dirk M. (WILEY-BLACKWELLMALDEN, 2012)

Literature data relevant to the decision to allow a waiver of in vivo bioequivalence (BE) testing for the approval of immediate-release (IR) solid oral dosage forms containing stavudine (d4T) are reviewed. According to ...

LC-UV Methodology for Simultaneous Determination of Lamivudine and Zidovudine in Plasma by Liquid-Liquid Extraction

SOUZA, Jacqueline De; KANO, Eunice Kazue; KOONO, Eunice Emiko Mori; SCHRAMM, Simone Grigoleto; PORTA, Valentina; STORPIRTIS, Silvia (VIEWEG, 2009)

This study describes an accurate, sensitive, and specific chromatographic method for the simultaneous quantitative determination of lamivudine and zidovudine in human blood plasma, using stavudine as an internal standard. ...

Acidosis láctica fatal en paciente con síndrome de inmunodeficiencia adquirido y tratamiento antiretroviral de alto grado de actividad: comunicación de un caso

Lasso B,Martín; Pérez G,Jorge; Noriega R,L. Miguel; Northland A,Rebeca (Sociedad Médica de Santiago, 2000)

Efectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine and lamivudine in HIV-1-infected adults in Cameroon: Open-label multicentre trial. Laurent C, Kovanfack C, Koulla-Shiro S, Nikové N et al. Lancet 2004; 364: 29-34

Calvo A.,Mario (Sociedad Chilena de Infectología, 2004)

A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy

Huanga, Wenlong; Calvo Bascuñan, Margarita; Karu, Kersti; Olausen, Hans R.; Bathgate, Gabriella; Okuse, Kenji; Bennett, David L. H.; Rice, Andrew S. C. (2013)

Stereoselective synthesis of azanucleosides aza-stavudine (aza-D4T), aza-2 ',3 '-didehydro-3 '-deoxyuridine (aza-D4U), and its hydrogenated analogues from an endocyclic enecarbamate

Costenaro, ER; Fontoura, LAM; Oliveira, DF; Correia, CRD (Pergamon-elsevier Science LtdOxfordInglaterra, 2001)

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Stavudine effects on rat pregnancy outcome

Effects of chronic stavudine exposure on liver, pancreas and kidneys of pregnant rats and their fetuses: Morphological and biochemical aspects

Effects of daily intake of zidovudine-stavudine on rat pregnancy outcome: biological essay

Effects of daily intake of zidovudine-stavudine on rat pregnancy outcome: biological essay

Biowaiver monographs for immediate-release solid oral dosage forms: Stavudine

LC-UV Methodology for Simultaneous Determination of Lamivudine and Zidovudine in Plasma by Liquid-Liquid Extraction

Acidosis láctica fatal en paciente con síndrome de inmunodeficiencia adquirido y tratamiento antiretroviral de alto grado de actividad: comunicación de un caso

Efectiveness and safety of a generic fixed-dose combination of nevirapine, stavudine and lamivudine in HIV-1-infected adults in Cameroon: Open-label multicentre trial. Laurent C, Kovanfack C, Koulla-Shiro S, Nikové N et al. Lancet 2004; 364: 29-34

A clinically relevant rodent model of the HIV antiretroviral drug stavudine induced painful peripheral neuropathy

Stereoselective synthesis of azanucleosides aza-stavudine (aza-D4T), aza-2 ',3 '-didehydro-3 '-deoxyuridine (aza-D4U), and its hydrogenated analogues from an endocyclic enecarbamate