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STAT3 Expression and Activity are Up-Regulated in Diffuse Large B Cell Lymphoma of Dogs
(Wiley-Blackwell, 2018-01-01)
Background: The Janus Kinase (JAK) and Signal Transducer and Activator of Transcription (STAT) pathways play important roles in the pathogenesis of diffuse large B cell lymphoma (DLBCL) in humans, and up-regulated STAT3 ...
Zinc deficiency affects the STAT1/3 signaling pathways in part through redox-mediated mechanisms
(Elsevier, 2017-04)
Zinc deficiency affects the development of the central nervous system (CNS) through mechanisms only partially understood. We previously showed that zinc deficiency causes CNS oxidative stress, damaging microtubules and ...
Estudo da participação de reguladores negativos endógenos da atividade de STAT1 e STAT3 (SOCS1 e SOCS3) na doença periodontal experimental
(Universidade Estadual Paulista (UNESP), 2014)
Progestins induce transcriptional activation of signal transducer and activator of transcription 3 (Stat3) via a Jak- and Src-dependent mechanism in breast cancer cells
(American Society for Microbiology, 2005-12)
Interactions between steroid hormone receptors and signal transducer and activator of transcription (Stat)-mediated signaling pathways have already been described. In the present study, we explored the capacity of progestins ...
Expression of suppressor of cytokine signaling 1 and 3 in ligature-induced periodontitis in rats
(Pergamon-Elsevier B.V. Ltd, 2011-10-01)
Objective: : Evaluate expression of inducible negative regulators of JAK/STAT pathway and their target proteins during the course of ligature-induced experimental periodontal disease in rats.Design: : Rats were sacrificed ...
Expression of suppressor of cytokine signaling 1 and 3 in ligature-induced periodontitis in rats
(Pergamon-Elsevier B.V. Ltd, 2011-10-01)
Objective: : Evaluate expression of inducible negative regulators of JAK/STAT pathway and their target proteins during the course of ligature-induced experimental periodontal disease in rats.Design: : Rats were sacrificed ...