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Translation and Silencing in RNA Granules: a Tale of Sand Grains
(Frontiers, 2014-07)
The transcriptome at the synapse consists of thousands of messengers encoding several cellular functions, including a significant number of receptors and ion channels and associated proteins. The concerted translational ...
Impaired eIF5A function causes a Mendelian disorder that is partially rescued in model systems by spermidine
(Nature, 2021)
The structure of proline prevents it from adopting an optimal position for rapid protein
synthesis. Poly-proline-tract (PPT) associated ribosomal stalling is resolved by highly conserved
eIF5A, the only protein to contain ...
Regulação da expressão do gene TcSof1 em Trypanosoma cruzi
(Instituto Carlos Chagas, 2014)