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Calcium-activated potassium channels
(Elsevier Ltd, 1998)
Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, ...
Dissection of K+ currents in Caenorhabditis elegans muscle cells by genetics and RNA interference
(NATL ACAD SCIENCES, 2003-11-25)
GFP-promoter experiments have previously shown that at least nine genes encoding potassium channel subunits are expressed in Caenorhabditis elegans muscle. By using genetic, RNA interference, and physiological techniques ...
Diversity of Potassium Channels in Human Umbilical Artery Smooth Muscle Cells: A Review of Their Roles in Human Umbilical Artery Contraction
(Sage Publications, 2014-04)
Through their control of cell membrane potential, potassium (K(+)) channels are among the best known regulators of vascular tone. This article discusses the expression and function of K(+) channels in human umbilical artery ...
SK2 channels are required for function and long-term survival of efferent synapses on mammalian outer hair cells
(Academic Press Inc Elsevier Science, 2009-01)
Cochlear hair cells use SK2 currents to shape responses to cholinergic efferent feedback from the brain. Using SK2-/- mice, we demonstrate that, in addition to their previously defined role in modulating hair cell membrane ...
Activation of endothelial transient receptor potential C3 channel is required for small conductance calcium-activated potassium channel activation and sustained endothelial hyperpolarization and vasodilation of cerebral artery
(John Wiley & Sons Inc, 2014-08)
BACKGROUND: Transient receptor potential C3 (TRPC3) has been demonstrated to be involved in the regulation of vascular tone through endothelial cell (EC) hyperpolarization and endothelium-dependent hyperpolarization-mediated ...
Differential effects of beta 1 and beta 2 subunits on BK channel activity
(ROCKEFELLER UNIV PRESS, 2005-04)
High conductance, calcium- and voltage-activated potassium (BK) channels are widely expressed in mammals. In some tissues, the biophysical properties of BK channels are highly affected by coexpression of regulatory (beta) ...
Inward rectifier potassium current I Kir promotes intrinsic pacemaker activity of thalamocortical neurons
(American Physiological Society, 2018-06)
Slow repetitive burst firing by hyperpolarized thalamocortical (TC) neurons correlates with global slow rhythms (<4 Hz), which are the physiological oscillations during non-rapid eye movement sleep or pathological oscillations ...