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Efeito antitumoral da berberina em linhagem de células SK-MEL-28 de melanoma
(Universidade Federal de Santa MariaBrasilBioquímicaUFSMPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica ToxicológicaCentro de Ciências Naturais e Exatas, 2022-01-10)
Melanoma is the most aggressive form of skin cancer, having high metastatic power, responsible for causing the majority (75%) of skin-related deaths. The metastatic power of tumor cells is a major challenge for therapeutic ...
Catecholamine effects on human melanoma cells evoked by α1-adrenoceptors
(2004-08-01)
The biological effects of catecholamines in mammalian pigment cells are poorly understood. Our previous results showed the presence of α1-adrenoceptors in SK-Mel 23 human melanoma cells. The aims of this work were to (1) ...
Selective cytotoxicity of PAMAM G5 core-PAMAM G2.5 shell tecto-dendrimers on melanoma cells
(Dove Press, 2012-07-31)
The controlled introduction of covalent linkages between dendrimer building blocks leads to polymers of higher architectural order known as tecto-dendrimers. Because of the few simple steps involved in their synthesis, ...
Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell
(Springer, 2016)
During the last two decades, new insights into proteasome function and its role in several human diseases made it a potential therapeutic target. In this context, Amblyomin-X is a Kunitz-type FXa inhibitor similar to ...