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Efeito do ácido rosmarínico sobre as crises epilépticas e alterações comportamentais em diferentes modelos experimentais de epilepsia
(Universidade Federal de Santa MariaBrasilFarmacologiaUFSMPrograma de Pós-Graduação em FarmacologiaCentro de Ciências da Saúde, 2016-03-01)
Epilepsy is a chronic neurological disease characterized by recurrent seizures. Current anticonvulsant
drugs are ineffective in nearly one third of patients and may cause significant adverse effects.
Rosmarinic acid is ...
Rosmarinic acid, a new snake venom phospholipase A(2) inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction
(Elsevier B.V., 2005-09-01)
Many plants are used in traditional medicine as active agents against various effects induced by snakebite. The methanolic extract from Cordia verbenacea (Cv) significantly inhibited paw edema induced by Bothrops jararacussu ...
Rosmarinic acid, a new snake venom phospholipase A(2) inhibitor from Cordia verbenacea (Boraginaceae): antiserum action potentiation and molecular interaction
(Elsevier B.V., 2005-09-01)
Many plants are used in traditional medicine as active agents against various effects induced by snakebite. The methanolic extract from Cordia verbenacea (Cv) significantly inhibited paw edema induced by Bothrops jararacussu ...
Elicitation improves rosmarinic acid content and antioxidant activity in Thymus lotocephalus shoot cultures
Thymus lotocephalus G. Lopez & R. Morales is an aromatic species endemic to the south of Portugal with medicinal properties. The aim of this work was to evaluate the effect of elicitors, cytokinin, and different sucrose ...
Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells
(Elsevier Sci LtdOxfordInglaterra, 2012)
Rosmarinic acid prevents fibrillization and diminishes vibrational modes associated to beta sheet in tau protein linked to Alzheimer’s disease
(Taylor & Francis, 2017)
Alzheimer’s disease is a common tauopathy where fibril formation and aggregates are the hallmark of the
disease. Efforts targeting amyloid-b plaques have succeeded to remove plaques but failed in clinical trials
to improve ...
Phenylpropanoids from Paspalum atratum (Poaceae)
(2015-12-01)
Nanoantioxidant–Based silica particles as flavonoid carrier for drug delivery applications
(MDPI, 2020)
Nanosystems used in pharmaceutical formulations have shown promising results in enhancing the administration of drugs of difficult formulations. In particular, porous silica nanoparticles have demonstrated excellent ...