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Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
(Elsevier B.V., 2002-10-11)
Here is described a structural model for the binary complex CDK5-roscovitine. Roscovitine has been shown to potently inhibit cyclin-dependent kinases 1, 2 and 5 (CDK1, 2, and 5), and the structure of CDK2 complexed with ...
Role of roscovitine and IBMX on kinetics of nuclear and cytoplasmic maturation of bovine oocytes in vitro
(Elsevier B.V., 2007-05-01)
The 3-isobutyl-1-methylxanthine (IBMX) is able to prevent resumption of meiosis by maintaining elevated cyclic AMP (cAMP) concentrations in the oocyte, and roscovitine, a purine known to specifically inhibit MPF kinase ...
Role of roscovitine and IBMX on kinetics of nuclear and cytoplasmic maturation of bovine oocytes in vitro
(Elsevier B.V., 2007-05-01)
The 3-isobutyl-1-methylxanthine (IBMX) is able to prevent resumption of meiosis by maintaining elevated cyclic AMP (cAMP) concentrations in the oocyte, and roscovitine, a purine known to specifically inhibit MPF kinase ...
Molecular model of cyclin-dependent kinase 5 complexed with roscovitine
(Elsevier B.V., 2014)
Molecular models of cyclin-dependent kinase 1 complexed with inhibitors
(Elsevier B.V., 2004-11-12)
Roscovitine and flavopiridol have been shown to potently inhibit cyclin-dependent kinase 1 and 2 (CDK1 and 2). The structures of CDK2 complexed with roscovitine and deschoroflavopiridol have been reported, however no ...
Molecular models of cyclin-dependent kinase 1 complexed with inhibitors
(Elsevier B.V., 2004-11-12)
Roscovitine and flavopiridol have been shown to potently inhibit cyclin-dependent kinase 1 and 2 (CDK1 and 2). The structures of CDK2 complexed with roscovitine and deschoroflavopiridol have been reported, however no ...
Parthenogenetic development of domestic cat oocytes treated with ionomycin, cycloheximide, roscovitine and strontium
(Elsevier B.V., 2010-09-01)
The objective was to evaluate the parthenogenetic activation of domestic cat oocytes. Cumulus-oocyte complexes matured for 36 h were subjected to three protocols of parthenogenetic activation: Group 1 - ionomycin + ...
Parthenogenetic development of domestic cat oocytes treated with ionomycin, cycloheximide, roscovitine and strontium
(Elsevier B.V., 2010-09-01)
The objective was to evaluate the parthenogenetic activation of domestic cat oocytes. Cumulus-oocyte complexes matured for 36 h were subjected to three protocols of parthenogenetic activation: Group 1 - ionomycin + ...
Meiotic arrest of sheep oocytes using roscovitine under different medium compositions
(Elsevier B.V., 2015-05-01)
Attempts to maintain the meiotic arrest under suitable culture conditions have been performed in order to improve the quality of oocytes in vitro matured. So, our study aimed to evaluate the potential of roscovitine, an ...
Effect of roscovitine and cycloheximide on ultrastructure of sheep oocytes
(2013-01-01)
It is believed the temporary meiosis arrest with roscovitine or cycloheximide may improve the in vitro developmental competence of oocytes in different animal species. However, little is known about the effects of these ...