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PYK2/PDZ-RhoGEF Links Ca(2+) Signaling to RhoA
(LIPPINCOTT WILLIAMS & WILKINS, 2009)
Objective-Ras homolog gene family member A (RhoA)/Rho-kinase-mediated Ca(2+) sensitization is a critical component of constrictor responses. The present study investigates how angiotensin II activates RhoA. Methods and ...
Investigação de vias de sinalização celular relacionadas às proteínas Rho GTPases RhoC e RhoA em leucemia mieloide aguda
(Universidade Federal de São Paulo, 2022-03)
A Leucemia Mieloide Aguda (LMA) é um grupo heterogêneo de neoplasias hematológicas que acomete principalmente idosos. Na LMA, a hematopoiese é desregulada e há acúmulo de células imaturas (blastos) na medula óssea e sangue ...
Multiple gene knock-down by a single lentiviral vector expressing an array of short hairpin RNAs
(Pontificia Universidad Católica de Valparaíso, 2006)
Mucor rouxii Rho1 protein; characterization and possible role in polarized growth
(Springer, 2007-04)
We have previously shown that protein kinase A of the medically important zygomycete Mucor rouxii participates in fungal morphology through cytoskeletal organization. As a first step towards finding the link between protein ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(TAYLOR & FRANCIS LTD, 2010)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
Number of expressed cancer/testis antigens identifies focal adhesion pathway genes as possible targets for multiple myeloma therapy
(Taylor & Francis Ltd, 2010-08-01)
Considering that the importance of cancer/testis (CT) antigens in multiple myeloma (MM) biology is still under investigation, the present study aimed to: (1) identify genes differentially expressed in MM using microarray ...
Detection of changes in mould cell wall stress-related gene expression by a novel reverse transcription real-time PCR method
(Elsevier Science, 2018-06)
The cell wall integrity (CWI) pathway is activated in response to cell wall stresses due to different food-related environments. Rho1 is one of the main regulators within such pathway. The objective of this work was to ...
Schistosoma mansoni: descoberta de novos genes e estudos de genômica funcional de uma RHO GTPase
(Universidade Federal de Minas GeraisUFMG, 2000-09-27)
Schistosoma mansoni is a digenetic trematode that causes schistosomiasis, a parasitic disease that constitutes an important public health problem in Brazil and in many other countries throughout the world. The S. mansoni ...