Now showing items 1-10 of 253
Rho/Rho kinase signal transduction pathway in cardiovascular disease and cardiovascular remodeling. La vía de señalización Rho/Rho-cinasa en la enfermedad y el remodelado cardiovascular.
(EDICIONES DOYMA S/L, 2005-08)
The small guanosine triphosphatase Rho and its target, Rho kinase, play important roles in both blood pressure regulation and vascular smooth muscle contraction. Rho is activated by agonists of receptors coupled to cell ...
O-GlcNAcylation contributes to the vascular effects of ET-1 via activation of the RhoA/Rho-kinase pathway
(OXFORD UNIV PRESS, 2011)
Aims Glycosylation with beta-N-acetylglucosamine (O-GlcNAcylation) is one of the most complex post-translational modifications. The cycling of O-GlcNAc is controlled by two enzymes: UDP-NAc transferase (OGT) and O-GlcNAcase ...
Rho-kinase activity is upregulated in the skeletal muscle of aged exercised rats
There is a gap in the knowledge regarding the regulation of glucose uptake in skeletal muscle during the development of insulin resistance in the elderly. Rho-Kinase (Rock) signaling has been demonstrated as a crucial ...
Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery
(Blackwell PublishingOxfordInglaterra, 2005)
Short-term effects of Y-27632, a rho-associated protein kinase inhibitor, on chromatin supraorganization and DNA amount in epithelial cells of the rat cornea and limbus
Purpose: To assess the short-term effects of instilling Y-27632, an inhibitor of Rho/Rho-associated protein kinases, on the chromatin supraorganization and DNA amount of corneal and limbal epithelial cells of healthy rats. ...
Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK
(Springer New York LLC, 2019)
Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract
(Pergamon-elsevier Science LtdOxfordInglaterra, 2007)
Focal adhesion kinase, RhoA, and p38 mitogen-activated protein kinase modulates apoptosis mediated by angiotensin II AT2 receptors
(Wiley-liss, Div John Wiley & Sons Inc, 2019-02)
Apoptosis plays an important role in cellular processes such as development, differentiation, and homeostasis. Although the participation of angiotensin II (Ang II) AT2 receptors (AT 2R) in cellular apoptosis is well ...