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Cardiac Remodeling Induced by All-Trans Retinoic Acid is Detrimental in Normal Rats
(2017-11-01)
Background/Aims: This study aimed to discern whether the cardiac alterations caused by retinoic acid (RA) in normal adult rats are physiologic or pathologic. Methods and Results: Wistar rats were assigned into four groups: ...
MyD88 and Retinoic Acid Signaling Pathways Interact to Modulate Gastrointestinal Activities of Dendritic Cells
(INST MATHEMATICAL STATISTICS, 2011)
Myd88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells
(INST MATHEMATICAL STATISTICS, 2011)
Retinoic acid promotes apoptosis and differentiation in photoreceptors by activating the p38 MAP kinase pathway
(Association For Research In Vision And Ophthalmology, 2013-04)
Purpose Retinoic acid (RA) has a critical role during development of the retina, controlling cell fate and differentiation. We here investigated RA effects on photoreceptor differentiation and apoptosis and the intracellular ...
IL-33 enhances retinoic acid signaling on CD4+ T cells
(Academic Press, 2016)
© 2016 Elsevier Ltd. Several molecules have been described as CD4+ T cells differentiation modulators and among them retinoic acid (RA) and more recently, IL-33, have been studied. Due to the similarities in T helper cell ...
Crosstalk Between Retinoic Acid and Sex-Related Genes Controls Germ Cell Fate and Gametogenesis in Medaka
(Frontiers Media Sa, 2021-01-18)
Sex determination (SD) is a highly diverse and complex mechanism. In vertebrates, one of the first morphological differences between the sexes is the timing of initiation of the first meiosis, where its initiation occurs ...
IL-33 enhances retinoic acid signaling on CD4+T cells
(Elsevier, 2016)
Several molecules have been described as CD4+ T cells differentiation modulators and among them retinoic acid (RA) and more recently, IL-33, have been studied. Due to the similarities in T helper cell skewing properties ...
Bone Morphogenetic Protein-4 Inhibits Corticotroph Tumor Cells: Involvement in the Retinoic Acid Inhibitory Action
(Endocrine Society, 2006-01)
The molecular mechanisms governing the pathogenesis of ACTH-secreting pituitary adenomas are still obscure. Furthermore, the pharmacological treatment of these tumors is limited. In this study, we report that bone morphogenetic ...
Retinoic acid induces nuclear FAK translocation and reduces breast cancer cell adhesion through Moesin, FAK, and Paxillin
(Elsevier Ireland, 2016-07-15)
Breast cancer is the most common malignancy in women, with metastases being the cause of death in 98%. In previous works we have demonstrated that retinoic acid (RA), the main retinoic acid receptor (RAR) ligand, is involved ...
Involvement of Protein Kinase C α and δ Activities on the Induction of the Retinoic Acid System in Mammary Cancer Cells
(Wiley, 2014-05)
It has been established that retinoids exert some of their effects on cell differentiation and malignant phenotype reversion through the interaction with different members of the protein kinase C (PKC) family. Till nowadays ...