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Deleterious effects of VEGFR2 and RET inhibition in a preclinical model of Parkinson’s disease
(Humana Press Inc., 2018)
High Iodine Concentration Attenuates RET/PTC3 Oncogene Activation in Thyroid Follicular Cells
(MARY ANN LIEBERT INC, 2009)
Background: Papillary thyroid carcinoma (PTC) is frequently associated with a RET gene rearrangement that generates a RET/PTC oncogene. RET/PTC is a fusion of the tyrosine kinase domain of RET to the 50 portion of a different ...
Effects of let-7 microRNA on Cell Growth and Differentiation of Papillary Thyroid Cancer
(NEOPLASIA PRESS, 2009)
Papillary thyroid carcinoma (PTC) is the most common endocrine malignancy and RET/PTC rearrangements represent key genetic events frequently associated to this cancer, enhancing proliferation and dedifferentiation by ...
Nociceptor-like rat dorsal root ganglion neurons express theangiotensin-II AT2 receptor throughout development
(Pergamon-Elsevier Science Ltd, 2016-09)
tAT2 receptor (AT2R) plays a functional role in foetal development. Its expression declines in most tissuessoon after birth but stays high in sensory areas of the adult nervous system. In the dorsal root ganglia (DRG)the ...
AGK::BRAF no carcinoma papilífero da tiroide pediátrico: investigação do mecanismo associado à agressividade tumoral e análise funcional
(Universidade Federal de São Paulo, 2023-03-31)
Introdução: O carcinoma papilífero da tireoide (CPT), apesar de ser raro em crianças e adolescentes, geralmente têm uma apresentação clínica mais agressiva nesta população do que o CPT em adultos, apresentando multifocalidade, ...
A ingestão de ácidos graxos trans, durante a gestação e lactação, modifica os mecanismos intracelulares envolvidos com a resposta inflamatória, na prole com 21 dias de vida
(Universidade Federal de São Paulo (UNIFESP), 2010-11-24)
Although lipids transfer through placenta is very limited, modification in dietary fatty acids can lead to implications in fetal and postnatal development. Trans fatty acid intake during gestation and lactation have been ...
Neurobiologia das reações de defesa: avaliação celular e comportamental de camundongos submetidos ao teste de exposição ao ratoNeurobiology of defensive reactions: cellular and behavioral evaluation of mice submitted to the rat exposure test
(Universidade Federal de UberlândiaBrasilPrograma de Pós-graduação em Biologia Celular e Estrutural Aplicadas, 2018)
O papel da inervação do tecido adiposo retroperitoneal na ativação simpática sistêmica e alterações cardiovasculares e metabólicas em modelo de obesidade experimental
(Universidade Federal de São Paulo (UNIFESP), 2019-01-31)
The predominance of obesity and overweight has been constantly increasing in developed and emerging countries due to the intake of high-fat foods and a sedentary lifestyle of choice, which makes obesity one of the most ...
Fish oil consumption prevents glucose intolerance and hypercorticosteronemy in footshock-stressed rats
(Biomed Central Ltd, 2011-05-11)
Background: Environmental stress plays an important role in the development of glucose intolerance influencing lipid and glucose metabolism through sympathetic nervous system, cytokines and hormones such as glucocorticoids, ...
Efeito da suplementação de ácidos graxos trans ou oligofrutose, durante a gestação e lactação, nas mães e prole com 90 dias de vida sobre o metabolismo e parâmetros inflamatórios
(Universidade Federal de São Paulo (UNIFESP), 2016-04-30)
Introduction. Adverse effects of the consumption of trans fatty acids (TFA) have been widely studied by the scientific community in the last. Previously, our group found that the intake of trans fatty acids (TFA) during ...