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The importance of drug repurposing in the field of antiepileptic drug development
(Springer, 2016)
Drug repurposing involves finding new therapeutic uses for existing drugs, including marketed, discontinued, shelved, and investigational drugs. The advantages of this strategy are many: reduced drug development timeline, ...
Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics
(Informa Healthcare, 2019-12)
Drug repurposing(or repositioning) implies finding new therapeutic indications for existingdrugs (including approved, failed, discontinued and experimental drugs), andrepresents a substantial percentage of recent drug ...
Aminoglycosides can be a better choice over macrolides in COVID-19 regimen: Plausible mechanism for repurposing strategy
In the current COVID-19 pandemic, prioritizing the immunity enhancers is equally important to anti-virals.
Defensins are the forgotten molecules that enhance the innate immunity against various microbes. Although
macrolides ...
Can drug repurposing strategies be the solution to the COVID-19 crisis?
(Taylor & Francis Ltd, 2020-12)
Introduction: The current COVID-19 pandemic has resulted in disastrous human and economic costs, mainly due to the absence of specific treatments to ameliorate the effects of this emerging viral disease. Complementary to ...
In silico approaches for drug repurposing in oncology: protocol for a scoping review of existing evidence
(Public Library of Science, 2022)
Leishmaniasis treatment: update of possibilities for drug repurposing
(Frontiers in BioScience, 2018)
The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies
(Bentham Science Publishers, 2018-09)
Chagas´ disease continues to be a challenging and neglected public health problem in many American countries. The etiologic agent, Trypanosoma cruzi, develops intracellularly in the mammalian host, which hinders treatment ...
Combating COVID-19: The role of drug repurposing and medicinal plants
Background:A novel corona virus-2 disease has spread to 213 countries and territories across the globe.
The corona pandemic has claimed more than 548,934 deaths worldwide till the evening of 8
th of July 2020
and the ...