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PIAS gamma controls stability and facilitates SUMO-2 conjugation to CoREST family of transcriptional co-repressors
(2018)
CoREST family of transcriptional co-repressors regulates gene expression and cell fate determination during development. CoREST co-repressors recruit with different affinity the histone demethylase LSD1 (KDM1A) and the ...
Effect of mutation at the interface of Trp-repressor dimeric protein: a steered molecular dynamics simulation
(2013)
The strength of key interfacial contacts that
stabilize protein–protein interactions have been studied by
computer simulation. Experimentally, changes in the
interface are evaluated by generating specific mutations ...
The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4
(Company of Biologists Ltd, 2001)
In the early Xenopus embryo, the Xiro homeodomain proteins of the Iroquois (Iro) family control the expression of proneural genes and the size of the neural plate. We report that Xiro1 functions as a repressor that is ...
A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor
(2020-07-01)
The arginine repressor (ArgR) regulates the expression of genes involved in arginine biosynthesis. Upon attaining a threshold concentration of arginine in the cytoplasm, the trimeric C-terminal domain of ArgR binds three ...
Jasmonatos en frutilla (Fragaria x ananassa): caracterización fisiológica y molecular de los componentes de la vía de biosíntesis y señalización, y análisis estructura-función de los represores JAZJasmonates in strawberry (Fragaria x ananassa): physiological and molecular characterization of biosynthesis and signaling pathways and structure-function analysis of JAZ repressors
(2018)
Jasmonates (JAs) are phytohormones regulating stress responses and developmental
processes. The role of JAs is well known in Arabidopsis, in which they control flavonoid compounds accumulation like anthocyanins, through ...