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Tyrosine binding and promiscuity in the arginine repressor from the pathogenic bacterium Corynebacterium pseudotuberculosis
(2016-07-08)
The arginine repressor (ArgR) regulates arginine biosynthesis in a number of microorganisms and consists of two domains interlinked by a short peptide; the N-terminal domain is involved in DNA binding and the C-terminal ...
Repressor element-1 silencing transcription/neuron-restrictive silencer factor is required for neural sodium channel expression during development of Xenopus
(2002)
The ability of neurons to fire rapid action potential relies on the expression of voltage-gated sodium channels; the onset of the transcription of genes that encode these channels occurs during early neuronal development. ...
The Wnt-activated Xiro1 gene encodes a repressor that is essential for neural development and downregulates Bmp4
(Company of Biologists Ltd, 2001)
In the early Xenopus embryo, the Xiro homeodomain proteins of the Iroquois (Iro) family control the expression of proneural genes and the size of the neural plate. We report that Xiro1 functions as a repressor that is ...
A single P115Q mutation modulates specificity in the Corynebacterium pseudotuberculosis arginine repressor
(2020-07-01)
The arginine repressor (ArgR) regulates the expression of genes involved in arginine biosynthesis. Upon attaining a threshold concentration of arginine in the cytoplasm, the trimeric C-terminal domain of ArgR binds three ...
PIAS gamma controls stability and facilitates SUMO-2 conjugation to CoREST family of transcriptional co-repressors
(2018)
CoREST family of transcriptional co-repressors regulates gene expression and cell fate determination during development. CoREST co-repressors recruit with different affinity the histone demethylase LSD1 (KDM1A) and the ...
A bHLH-type transcription factor, JA-ASSOCIATED MYC2-LIKE1, acts as repressor to negatively regulate jasmonate signaling in Arabidopsis
(American Society of Plant Biologist, 2013-05)
Jasmonates (JAs) are plant hormones that regulate the balance between plant growth and responses to biotic and abiotic stresses. Although recent studies have uncovered the mechanisms for JA-induced responses in Arabidopsis ...
Regulation of carotenogenesis in the red yeast Xanthophyllomyces dendrorhous: the role of the transcriptional co-repressor complex Cyc8-Tup1 involved in catabolic repression
(Biomed Central, 2016)
Background: The yeast Xanthophyllomyces dendrorhous produces carotenoids of commercial interest, including astaxanthin and beta-carotene. Although carotenogenesis in this yeast and the expression profiles of the genes ...
Transcriptional regulation of the anthocyanin biosynthesis pathway in developing grapevine berries in cultivar "Malbec" by putative R2R3 MYB negative regulators
(Elsevier Science, 2019-11)
In grapevine, proanthocyanins (PAs) and anthocyanins are obtained via the phenylpropanoid pathway. These metabolites are synthesized in specific tissues of the berry and accumulate in different developmental stages. The ...