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A quantitative chemiluminescent method for studying replicative and stress-induced premature senescence in cell cultures
(ACADEMIC PRESS INC ELSEVIER SCIENCE, 2008)
beta-Galactosidase (beta-Gal) activity is a widely accepted biomarker to detect senescence both in situ and in vitro. A cytochemical assay based on production of a blue-dyed precipitate that results from the cleavage of ...
Increased production of functional small extracellular vesicles in senescent endothelial cells
(Wiley, 2020)
Small extracellular vesicles (EVs) are novel players in vascular biology. However, a thorough understanding of their production and function remains elusive. Endothelial senescence is a key feature of vascular ageing and ...
Homeostasis of DNA integrity
(2017-01-01)
Homeostasis comprises the tendency of an organism or cell to regulate their chemical processes that take place internally so as to maintain health, vital functions and stability, owing to the coordinated response of its ...
Modelagem lógica de senescência celular humana
(Universidade Federal de Santa MariaBRFísicaUFSMPrograma de Pós-Graduação em Física, 2012-12-12)
After the progressive telomere shortening in successive cell divisions, normal
somatic cells undergo a growth arrest called cellular senescence that occurs due to
incomplete DNA replication. Senescence can also be activated ...
Benzyladenine sprays and senescent flowers removal on postproduction performance of Potted zinnia 'Profusion cherry'
(2005-12-01)
'Profusion Cherry' is a dwarf zinnia with prospect for pot use in Brazil. The success of flowering potted plants depends on its performance during transport and on the period of time that it performs well indoors. Benzyladenine ...
Benzyladenine sprays and senescent flowers removal on postproduction performance of Potted zinnia 'Profusion cherry'
(2005-12-01)
'Profusion Cherry' is a dwarf zinnia with prospect for pot use in Brazil. The success of flowering potted plants depends on its performance during transport and on the period of time that it performs well indoors. Benzyladenine ...
Chronic in vitro exposure to 3′-azido-2′, 3′-dideoxythymidine induces senescence and apoptosis and reduces tumorigenicity of metastatic mouse mammary tumor cells
(Springer, 2001-03)
Normal cells in culture divide a certain amount of times and undergo a process termed replicative senescence. Telomere loss is thought to control entry into senescence. Activation of telomerase in tumors bypasses cellular ...
The role of HDL and phospholipids in endothelial cellular senescence
(Instituto Tecnológico y de Estudios Superiores de Monterrey, 2021-05-26)
High-density lipoproteins (HDLs) are commonly recognized as antiatherogenic molecules; these possess anti-inflammatory properties and participate in the production of Nitric Oxide (NO) by endothelial cells. In addition, ...