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Estimation of the Minimum Number of Replication Origins Per Chromosome in any Organism
(Bio-protocol, 2020-10-20)
Eukaryote nuclear genomes predominantly replicate through multiple replication origins. The number of replication origins activated per chromosome during the S-phase duration may vary according to many factors, but the ...
Molecular characterization of IPNV RNA replication intermediates during the viral infective cycle
(2009)
Infectious Pancreatic Necrosis Virus (IPNV) is a bisegmented, double-stranded RNA virus, which belongs to the Birnaviridae family. In the current study, we have analyzed the RNA replication intermediates (RI) purified ...
Antiviral activity of phosphonoformate on rotavirus transcription and replication
(1995)
The antiviral effect of foscarnet (PFA) on the replication of rotavirus, a member of the Reoviridae, was studied. The pyrophosphate analogue is an effective inhibitor of several viral polymerases acting on the enzyme ...
Plant chromatin replicated in the absence of protein synthesis
(1983)
The aim of the present work is to detect possible differences in the chromatin of plants replicated in the absence of protein synthesis.The kinetics of nuclease digestion in Allium cepa L., evaluated after making the cells ...
Hepatitis C virus in vitro replication is efficiently inhibited by acridone Fac4
(2017-07-01)
Hepatitis C virus (HCV) affects about 170 million people worldwide. The current treatment has a high cost and variable response rates according to the virus genotype. Acridones, a group of compounds extracted from natural ...