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Mostrando ítems 1-10 de 21
Next-generation technologies and systems biology for the design of novel vaccines against apicomplexan parasites
(Frontiers Media, 2022-01)
Parasites of the phylum Apicomplexa are the causative agents of important diseases such as malaria, toxoplasmosis or cryptosporidiosis in humans, and babesiosis and coccidiosis in animals. Whereas the first human recombinant ...
Generation of a multi‑herbicide‑tolerant alfalfa by using base editing
(Springer, 2022-02)
We present the first report on base editing in alfalfa. Specifically, we showed edited alfalfa with tolerance to both sulfonylurea- and imidazolinone-type herbicides. Alfalfa (Medicago sativa) is one of the most important ...
The Gln15Arg mutation in the transcriptional factor PALM1 produces multifoliate alfalfa
(Springer, 2022-12)
The CRISPR/Cas9 system has proven to be highly valuable for genome editing in several important crops, including the allogamous tetraploid cultivated alfalfa (Medicago sativa). However, the fact that most of the beneficial ...
Expanding the benefits of Tnt1 for the identification of dominant mutations in polyploid crops: A single allelic mutation in the MsNAC39 gene produces multifoliated alfalfa
(Frontiers Media, 2022-04)
Most major crops are polyploid species and the production of genetically engineered cultivars normally requires the introgression of transgenic or gene-edited traits into elite germplasm. Thus, a main goal of plant research ...
CRISPR/Cas9‑mediated knockout of SPL13 radically increases lettuce yield
(Springer, 2022-12)
Cultivated lettuce (Lactuca sativa L.) is a diploid (2n = 2x = 18), autogamous species. This popular leafy vegetable is considered one of the first crops (Guo et al. 2022). Currently, lettuce is the third most consumed ...
Balance between retroviral latency and transcription : based on HIV model
(MDPI, 2021-01)
The representative of the Lentivirus genus is the human immunodeficiency virus type 1 (HIV-1), the causative agent of acquired immunodeficiency syndrome (AIDS). To date, there is no cure for AIDS because of the existence ...
Genomic editing with CRISPR/Cas9: Nobel Prize in Chemistry 2020Edición genómica con CRISPR/Cas9: Premio Nobel de Química 2020
(Pontificia Universidad Católica del Perú, 2021)
Aplicaciones y perspectivas de la edición génica de plantas mediante CRISPR-Cas9 = Applications and perspectives of plant gene editing using CRISPR-Cas9
(Universidad de Morón, 2022)
Los avances en materia de genética y biotecnología, introducen una dimensión novedosa en la utilización de herramientas de edición génica en plantas. En el presente trabajo se relevaron 164 publicaciones científicas que ...
Edición génica con el sistema CRISPR/Cas9: historia de su descubrimiento y alcances en agricultura
(Universidad de Los Andes, Venezuela, 2021-04)
La conversión del sistema inmune procariota CRISPR/Cas9 en una herramienta molecular para edición génica representa el avance tecnológico más destacado de la última década, y ha revolucionado tanto la investigación básica ...
Edición genómica con CRISPR/Cas9: Premio Nobel de Química 2020Genomic editing with CRISPR/Cas9: Nobel Prize in Chemistry 2020
(Pontificia Universidad Católica del PerúPE, 2021)