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Renin-angiotensin system as a potential target for new therapeutic approaches in Parkinson’s disease
(Taylor and Francis Ltd, 2017)
Angiotensin-(1-9) reduces cardiovascular and renal inflammation in experimental renin-independent hypertension
(Elsevier Inc., 2018)
© 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
Diversity of pathways for intracellular angiotensin II synthesis
(Lippincott Williams & Wilkins, 2009-01-01)
Purpose of reviewThe renin-angiotensin system (RAS) has undergone continuous advancement since the initial identification of renin as a pressor agent. Traditionally considered a circulatory system, the RAS is now known to ...
Precision Medicine in the Renin Angiotensin System Therapeutic Targets and Biological Variability
(Bentham Science Publishers, 2020-07)
Abstract: Pathologies linked to the renin angiotensin system are frequent, and the drugs used in them are numerous and show great variability in therapeutic effects and adverse reactions. Genetic variants have been detected ...
Vaccines against components of the renin-angiotensin system
(Springer, 2020)
Even though effective drugs for treating hypertension are available, a great percentage of patients have inadequate control of their blood pressure. Unwanted side effects and inappropriate oral drug adherence are important ...
Differential regulation of the renin-angiotensin system by nicotine in WKY and SHR glia
(HUMANA PRESS INC, 2008)
Given that (1) the renin-angiotensin system (RAS) is compartmentalized within the central nervous system in neurons and glia (2) the major source of brain angiotensinogen is the glial cells, (3) the importance of RAS in ...
Alternative pathways for angiotensin II generation in the cardiovascular system
(Associação Brasileira de Divulgação Científica, 2011)
The classical renin-angiotensin system (RAS) consists of enzymes and peptides that regulate blood pressure and electrolyte and fluid homeostasis. Angiotensin II (Ang II) is one of the most important and extensively studied ...
Modulation of the renin-angiotensin-aldosterone system in sepsis: a new therapeutic approach?
(Informa Healthcare, 2010-01-01)
Importance of the field: Severe sepsis is characterized by relative hypotension associated with a high cardiac output, peripheral vasodilation, and organ dysfunction. the renin-angiotensin-aldosterone system (RAAS) is ...