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Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats

Universidade Estadual Paulista (Unesp) (2017-03-01)

Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced ...

Naringin, trimetazidine and baroreflex in renal ischemia-reperfusion injuryNaringina, trimetazidina e barorreflexo na lesão de isquemia e reperfusão renal

Universidade Estadual Paulista (UNESP) (2021-01-01)

Increased resistance against oxidative stress is observed during a short period of renal reperfusion after a temporal ischaemia

Campos, Rolando; Garrido, Argelia; Guerra, Ricardo; Valenzuela Bonomo, Carlos (Informa Healthcare, 1990)

Reperfusion of rat kidney submitted to temporal ischaemia induces a decrease in glutathione content. Lipid peroxidation is not detected in kidney homogenates but microsomes obtained after periods of reperfusion longer than ...

Aminoguanidine Prevents the Oxidative Stress, Inhibiting Elements of Inflammation, Endothelial Activation, Mesenchymal Markers, and Confers a Renoprotective Effect in Renal Ischemia and Reperfusion Injury

Pasten, Consuelo; Lozano, Mauricio; Rocco, Jocelyn; Carrión, Flavio; Alvarado Livacic, Cristobal; Liberona, Jéssica; Michea, Luis; Irarrázabal, Carlos (Antioxidants, 2022)

Protective effect of D-003 on renal ischemia-reperfusion in rats

Carbajal, Daisy; Noa, Miriam; Ravelo, Yazmin; Arruzazabala, María de Lourdes; Más, Rosa; Valle, Maikel; Mendoza, Nilda (2009)

Parecoxib reduces renal injury in an ischemia/reperfusion model in rats

Universidade Estadual Paulista (Unesp) (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015-04-01)

To evaluate the effect of parecoxib (an NSAID) on renal function by measuring plasma NGAL (serum neutrophil gelatinase-associated lipocalin) levels in an induced-ischemia rat model. METHODS: Forty male Wistar rats were ...

Effects of Ischemic Preconditioning and Postconditioning in a Renal Ischemia-Reperfusion Injury Model: A Comparative Experimental Study in Rats

Universidade Estadual Paulista (Unesp); ABC Med Sch (Elsevier B.V., 2018-12-01)

Background. Ischemia-reperfusion injury is an unavoidable aspect of transplantation, as well as an important cause of acute kidney injury in clinical practice. Pre- and post-ischemic conditioning are strategies that may ...

Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury

Feitoza, C. Q.; Camara, NOS; Pinheiro, H. S.; Goncalves, G. M.; Cenedeze, M. A.; Pacheco-Silva, A.; Santos, OFP (Elsevier B.V., 2005-01-01)

Ischemia-reperfusion injury (IRI) is a common event in organ transplantation. being implicated as a potential contributor for the development of chronic allograft nephropathy. There are new evidences showing a tissue ...

Renal ischemia and reperfusion injury: influence of chorpromazine on renal function and lipid peroxidation

TUCCI JUNIOR, Silvio; CARVALHO, Roberto Marins de; CELINI, Fábia Martins; COLOGNA, Adauto José; SUAID, Haylton Jorge; TIRAPELLI, Luis Fernando; MARTINS, Antonio Carlos Pereira (Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2008)

PURPOSE: To evaluate the influence of chlorpromazine (CPZ) on renal function and lipid peroxidation in a rat model of kidney ischemia/reperfusion injury. METHODS: Forty eight Wistar rats underwent a laparotomy for hilar ...

Pharmacological treatment with galectin-1 protects against renal ischaemia-reperfusion injury

Universidade Estadual Paulista (Unesp); FACERES School of Medicine Brazil; Universidade de São Paulo (USP) (2018-12-01)

Galectin-1 protein (GAL-1) has important anti-inflammatory properties, but related pharmacologic approaches to effectively treat or prevent renal ischaemia and reperfusion injury are highly limited. Here, we investigated ...

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