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Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats
(2017-03-01)
Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced ...
Parecoxib reduces renal injury in an ischemia/reperfusion model in rats
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2015-04-01)
To evaluate the effect of parecoxib (an NSAID) on renal function by measuring plasma NGAL (serum neutrophil gelatinase-associated lipocalin) levels in an induced-ischemia rat model. METHODS: Forty male Wistar rats were ...
Effects of Ischemic Preconditioning and Postconditioning in a Renal Ischemia-Reperfusion Injury Model: A Comparative Experimental Study in Rats
(Elsevier B.V., 2018-12-01)
Background. Ischemia-reperfusion injury is an unavoidable aspect of transplantation, as well as an important cause of acute kidney injury in clinical practice. Pre- and post-ischemic conditioning are strategies that may ...
Evaluation of stem cell administration in a model of kidney ischemia-reperfusion injury
(Elsevier B.V., 2007-12-15)
Ischemia-reperfusion injury is a common early event in kidney transplantation and contributes to a delay in organ function. Acute tubular necrosis, impaired kidney function and organ leukocyte infiltration are the major ...
Dexmedetomidine on renal ischemia-reperfusion injury in rats: assessment by means of NGAL and histology
(Informa Healthcare, 2015-04-01)
Background: Ischemic acute kidney injury is a common occurrence in the perioperative period and in critical patients admitted to intensive care units. The reestablishment of blood supply may worsen injury through the ...
Does propofol and isoflurane protect the kidney against ischemia/reperfusion injury during transient hyperglycemia?
(Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia, 2013-03-01)
PURPOSE: To study the effect of isoflurane (Iso) or propofol (Prop) anesthesia on renal ischemia/reperfusion injury (IRI) during transient hyperglycemia. METHODS: Thirty six rats were randomly assigned into six groups of ...
Cyclooxygenase 1 and/or 2 blockade ameliorates the renal tissue damage triggered by ischemia and reperfusion injury
(Elsevier B.V., 2005-01-01)
Ischemia-reperfusion injury (IRI) is a common event in organ transplantation. being implicated as a potential contributor for the development of chronic allograft nephropathy. There are new evidences showing a tissue ...
Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats
(SPRINGER, 2011)
Inflammation is currently recognized as a key mechanism in the pathogenesis of renal ischemia-reperfusion (I/R) injury. The importance of infiltrating neutrophil, lymphocytes, and macrophage in this kind of injury has been ...
Annexin 1 mimetic peptide protects against renal ischemia/reperfusion injury in rats
(Springer, 2011-01-01)
Inflammation is currently recognized as a key mechanism in the pathogenesis of renal ischemia-reperfusion (I/R) injury. The importance of infiltrating neutrophil, lymphocytes, and macrophage in this kind of injury has been ...