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Parafoveal letter recognition at reduced contrast in normal aging and in patients with risk factors for AMD
(SPRINGER, 2009)
Background Patients with early age-related maculopathy ( ARM) do not necessarily show obvious morphological signs or functional impairment. Many have good visual acuity, yet complain of decreased visual performance. The ...
Basic Concepts on the Role of Nuclear Factor Erythroid-Derived 2-Like 2 (Nrf2) in Age-Related Diseases
(Mdpi, 2019-07-01)
The transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) is one of the most important oxidative stress regulator in the human body. Once Nrf2 regulates the expression of a large number of cytoprotective ...
Influence of BDNF Genetic Polymorphisms in the Pathophysiology of Aging-related Diseases
(Int Soc Aging & Disease, 2020)
For the first time in history, most of the population has a life expectancy equal or greater than 60 years. By the year 2050, it is expected that the world population in that age range will reach 2000 million, an increase ...
Incentive relativity in middle aged rats
(Elsevier Ireland, 2014-01)
Response to a reinforcer is affected by prior experience with different reward values of that reward, a phenomenon known as incentive relativity. Two different procedures to study this phenomenon are the incentive downshift ...
Exercise training as a preventive tool for age-related disorders: a brief review
(Universidade de São Paulo (USP), Faculdade de Medicina, 2013-05-01)
Aging populations are a worldwide phenomenon affecting both developed and developing countries. This issue raises serious concerns for both governments and the general population. Regular participation in physical activity ...
Aerobic exercise prevents age-dependent cognitive decline and reduces anxiety-related behaviors in middle-aged and old rats
(Pergamon-Elsevier Science Ltd, 2012-01)
Recent research involving human and animals has shown that aerobic exercise of moderate intensity produces the greatest benefit on brain health and behavior. In this study we investigated the effects on cognitive function ...