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Adverse outcome pathways - development and potential regulatory application
(Fundacao Oswaldo Cruz, Inst Nacional Controle Qualidade & Saude, 2021-08-01)
Introduction: Over the last two decades, chemical safety assessment and regulatory toxicology have progressed from empirical science based on direct observation of apical adverse outcomes in whole organisms to a predictive ...
The gap gene giant of Rhodnius prolixus is maternally expressed and required for proper head and abdomen formation
(Academic Press Inc Elsevier Science, 2012-01)
The segmentation process in insects depends on a hierarchical cascade of gene activity. The first effectors downstream of the maternal activation are the gap genes, which divide the embryo in broad fields. We discovered a ...
Regulation of Connexin-based channels by fatty acids
(Frontiers Research Foundation, 2017)
ENVIRONMENTAL REFUGEES AND THE ACTION OF UNHCR AS AN INTERNATIONAL PROTECTION ORGANISMREFUGIADOS AMBIENTAIS E A ATUAÇÃO DO ACNUR COMO ORGANISMO INTERNACIONAL DE PROTEÇÃO
(Universidade Federal de Santa Maria, 2016)
Rule-takers, rule-makers, or rule-promoters? Turkey and Mexico's role as rising middle powers in global economic governance
(WILEY, 2019)
Rising middle powers play increasingly active international roles, yet so far we lack systematic analyses of their aspirations and impact on global economic governance. This paper addresses this gap. I argue that the role ...
Connexin-Mediated Signaling at the Immunological Synapse
(MDPI, 2020)
The immunological synapse (IS) is an intercellular communication platform, organized at the contact site of two adjacent cells, where at least one is an immune cell. Functional IS formation is fundamental for the modulation ...