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A comparative analysis of heart microRNAs in vertebrates brings novel insights into the evolution of genetic regulatory networks
(2021-12-01)
Background: During vertebrate evolution, the heart has undergone remarkable changes that lead to morphophysiological differences in the fully formed heart of these species, such as chamber septation, heart rate frequency, ...
Exploring in silico transcriptional and post-transcriptional gene regulatory networks in the Corynebacterium genus
(Universidade Federal de Minas GeraisBrasilICB - DEPARTAMENTO DE BIOLOGIA GERALPrograma de Pós-Graduação em BioinformaticaUFMG, 2021-05-27)
Transcriptional and post-transcriptional regulation of gene expression are considered key regulatory steps in bacteria. Regulatory molecules such as transcription factors (TF), sigma-factors and small RNAs (sRNAs) modulate ...
Neighboring gene regulation by antisense long Non-Coding RNAs
(2015)
Antisense transcription, considered until recently as transcriptional noise, is a very common phenomenon in human and eukaryotic transcriptomes, operating in two ways based on whether the antisense RNA acts in cis or in ...
A regulatory RNA is involved in RNA duplex formation and biofilm regulation in sulfolobus acidocaldarius
(Oxford University Press, 2018-05-18)
Non-coding RNAs (ncRNA) are involved in essential biological processes in all three domains of life. The regulatory potential of ncRNAs in Archaea is, however, not fully explored. In this study, RNA-seq analyses identified ...
MicroRNAs and the neural crest: From induction to differentiation
(Elsevier Science, 2018-12)
MicroRNAs are small noncoding RNAs that can control gene expression by base pairing to partially complementary mRNAs. Regulation by microRNAs plays essential roles in diverse biological processes such as neural crest ...
Análise exploratória em larga escala de microRNAs expressos em tilápia do Nilo utilizando ferramentas de bioinformática
(Universidade Estadual Paulista (Unesp), 2016-12-12)
MicroRNAs (miRNAs) são pequenas moléculas de RNA que regulam pós-transcricionalmente a expressão de genes, modelando o transcriptoma e a produção de proteínas. Em geral, os miRNAs são conservados no genoma de eucariotos, ...
Perfil global de expressão de micro-RNAs no músculo esquelético de ratos com insuficiência cardíaca
(Universidade Estadual Paulista (Unesp), 2013-05-17)
MicroRNAs (miRNAs) constituem uma classe de pequenos RNAs não codificadores de 17 a 25 nucleotídeos de comprimento envolvidos em uma grande variedade de processos celulares. Os microRNAs regulam a expressão gênica ...