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An anti-human recombinant tumor necrosis factor alpha (TNFα) monoclonal antibody recognizes an epitope in feline TNFα
(EDP Sciences, 2003)
It is likely that the murine response to human recombinant TNFα (hrTNFα) may generate antibodies (Ab) to epitopes present in TNFα from other species. Here, we demonstrate that F5 anti-hrTNFα monoclonal antibody (mAb) ...
Therapeutic monoclonal antibodies: scFv patents as a marker of a new class of potential biopharmaceuticals
(Universidade de São Paulo, Faculdade de Ciências Farmacêuticas, 2011)
Monoclonal antibodies represent the fastest growing class of biopharmaceutical products and have a host of applications in medical research, diagnosis, therapy, and basic science. The production of recombinant monoclonal ...
Biosimilar monoclonal antibodies in Latin America
(IntechOpen, 2021)
Antibodies, also known as immunoglobulins, are complex glycoproteins produced by B-cells against foreign substances as part of the adaptive immune response [1, 2]. The invention of the hybridoma technology in 1975 by Köhler ...
Establishment and evaluation of a transient expression method in Expi293F system for Fab monoclonal antibody fragment production
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2019)
Production of monoclonal antibodies and development of a quantitative immuno-polymerase chain reaction assay to detect and quantify recombinant Glutathione S-transferase
(Academic Press Inc Elsevier Science, 2017-07)
GST-tagged proteins are important tools for the production of recombinant proteins. Removal of GST tag from its fusion protein, frequently by harsh chemical treatments or proteolytic methods, is often required. Thus, the ...
In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom.
(2022)
The monocled cobra (Naja kaouthia) is among the most feared snakes in Southeast Asia due to its toxicity, which is predominantly derived from long-chain α-neurotoxins. The only specific treatment for snakebite envenoming ...
Clonagem e expressão da glicoproteína transmembrana do vírus linfotrópico de células T humanas em sistema procarioto
(2007-05-01)
HTLV-1 is the virus that causes T cell lymphoma/leukemia in adults and a neurological disorder known as HTLV-associated myelopathy or tropical spastic paraparesis. One of the transmission means is through contaminated blood ...