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Hepatic overexpression of sterol carrier protein-2 inhibits VLDL production and reciprocally enhances biliary lipid secretion
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2003)
We examined in vivo a role for sterol carrier protein-2 (SCP-2) in the regulation of lipid secretion across the hepatic sinusoidal and canalicular membranes. Recombinant adenovirus Ad.rSCP2 was used to overexpress SCP-2 ...
Glucose regulates steady-state levels of PDX1 via the reciprocal actions of GSK3 and AKT kinases
(American Society for Biochemistry and Molecular Biology, 2010-01)
The pancreatic beta cell is sensitive to even small changes in PDX1 protein levels; consequently, Pdx1 haploinsufficiency can inhibit beta cell growth and decrease insulin biosynthesis and gene expression, leading to ...
Interrogating interneurone function using threshold tracking of the H reflex in healthy subjects and patients with motor neurone disease
(Elsevier, 2020)
Objective: The excitability of the lower motoneurone pool is traditionally tested using the H
reflex and a constant-stimulus paradigm, which measures changes in the amplitude of the reflex
response. This technique has ...