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Reconstitution of the steroid receptor heterocomplex
(Humana Press, 2019-03)
Steroid receptors are members of a subfamily of the nuclear receptor superfamily. They play a dual role of steroid hormone receptors and transcription factors. Actually, these receptors are steroid-activated transcription ...
Structure-activity relationships of neuroactive steroids acting on the GABAA receptor
(Bentham Science Publishers, 2009-12)
The term "neuroactive steroid" (NAS) refers to steroids which, independent of their origin, are capable of modifying neural activities. These steroids positively or negatively modulate the function of members of the ...
Excess androgen during perinatal life alters steroid receptor expression, apoptosis, and cell proliferation in the uteri of the offspring
(2013-09-01)
Exposure to environmental chemicals may contribute to reproductive disorders, especially when it occurs in critical periods of development. The female reproductive system can be a target for androgens derived from environmental ...
Excess androgen during perinatal life alters steroid receptor expression, apoptosis, and cell proliferation in the uteri of the offspring
(2013-09-01)
Exposure to environmental chemicals may contribute to reproductive disorders, especially when it occurs in critical periods of development. The female reproductive system can be a target for androgens derived from environmental ...
Steroids differentially inhibit the nicotinic acetylcholine receptor
(Lippincott Williams, 2001-12-02)
The effect of various natural and synthetic steroids on the function of the nicotinic acetylcholine receptor (AChR) was studied at the single-channel level. AChR channel kinetics was affected by some substitutions in the ...
Molecular chaperones shape steroid receptor action and pharmacologic strategies
(Jacobs Publisher, 2015-03-31)
Chaperone oligomers exist in cell cytosols as preassembled heterocomplexes that function as protein-folding molecular machines able to assemble essential proteins related to families that embrace steroid receptors, ...
SEX STEROID-RECEPTORS in POLYCYSTIC OVARIES
(Elsevier B.V., 1993-09-01)
Introduction to the Special Issue “Neuroactive Steroids”
(Springer/Plenum Publishers, 2019-09)
Steroids are complex molecules, exerting known and still unknown effects in the nervous system. Throughout this volume, the reader will find a wide spectrum of articles, giving an up-to-date account of the molecular, ...