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Modeling SDF-1–induced mobilization in leukemia cell lines
(Elsevier BV, 2020)
Differential expression of SDF-1 receptor CXCR4 in molecularly defined forms of inherited thrombocytopenias
(Taylor & Francis Ltd, 2016-12)
The SDF-1-CXCR4 axis plays an essential role in the regulation of platelet production, by directing megakaryocyte (MK) migration toward the vascular niche, thus allowing terminal maturation and proplatelet formation, and ...
Thalidomide treatment down-regulates SDF-1 alpha and CXCR4 expression in multiple myeloma patients
(PERGAMON-ELSEVIER SCIENCE LTD, 2009)
The chemokine stromal-derived factor-1 alpha (SDF-1 alpha) and its receptor CXCR4 are critically involved in directional migration and homing of plasma cells in multiple myeloma. Here, we show that the expression of SDF-1 ...
Stromal-derived factor-1 alpha (CXCL12) levels increase in periodontal disease
(AMER ACAD PERIODONTOLOGY, 2008)
Background: The CXC chemokine receptor 4 (CXCR4) and its ligand, stromal cell-derived factor-1 (SDF-1 alpha or CXC chemokine ligand 12) are involved in the trafficking of leukocytes into and out of extravascular tissues. ...
Distribution of SDF1-3'A polymorphisms in three different ethnic groups from Brazil
(Scielo, 2010-04)
A mutation described as a G-to-A transition has been reported in SDF-1 gene (SDF1-3'A), being prevalent in all ethnic groups, except in Africans. This mutation is associated with the onset of AIDS progression. Our aim was ...
Rol del eje de sensibilización SDF-1a/CXCR4b en la retención de los neutrófilos durante el desarrollo y la respuesta inflamatoria
(Universisdad de Chile, 2014)
La quimioquina SDF-la (CXCL12) se expresa constitutivamente en el tejido hematopoyetico por las células estromales, En este tejido se encuentra participando como señal quimiotactica y de retención para las células trancales ...
Better CD4+T Cell Recovery in Brazilian HIV-Infected Individuals Under HAART Due to Cumulative Carriage of SDF-1-3`A, CCR2-V64I, CCR5-D32 and CCR5-Promoter 59029A/G Polymorphisms
(BENTHAM SCIENCE PUBL LTD, 2008)
Polymorphisms of chemokines and chemokine-receptors genes have been shown to influence the rate of progression to AIDS; however, their influence on response to HAART remains unclear. We investigated the frequency of the ...
Protective effect of CCR2-64I and not of CCR5-Δ32 and SDF1-3'A in pediatric HIV-1 infection
(Lippincott Williams, 2000)