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N-domain angiotensin-converting enzyme isoform expression in tissues of Wistar and spontaneously hypertensive rats
(Lippincott Williams & Wilkins, 2005-10-01)
Background Angiotensin I-converting enzyme (ACE) is a protein containing two active sites, called N- and C-domains, according to their position in the protein.Aim the aim of the present study was to verify whether the ...
Dietary Potassium Downregulates Angiotensin-I Converting Enzyme, Renin, and Angiotensin Converting Enzyme 2
(2020-06-18)
Background: The importance of dietary potassium in health and disease has been underestimated compared with that placed on dietary sodium. Larger effort has been made on reduction of sodium intake and less on the adequate ...
A continuous fluorescent assay for the determination of plasma and tissue angiotensin I-converting enzyme activity
(Associação Brasileira de Divulgação Científica, 2005-06-01)
A continuous assay using internally quenched fluorescent peptides with the general sequence Abz-peptidyl-(Dnp)P-OH (Abz = ortho-aminobenzoic acid; Dnp = 2,4-dinitrophenyl) was optimized for the measurement of angiotensin ...
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
(LIPPINCOTT WILLIAMS & WILKINS, 2001-09)
Angiotensin I is a substrate for both ACE and for neutral endopeptidase 24.11 (NEP). We hypothesized that high ACE expression is related to low NEP activity. Accordingly, circulating and tissue NEP and ACE activities were ...
ACE2 and ANG-(1-7) in the rat uterus during early and late gestation
(AMER PHYSIOLOGICAL SOC, 2008)
The present study was designed to determine ANG peptide content [ANG I, ANG II, ANG( 1-7)], ACE2 mRNA, and the immunocytochemical distribution of ANG-(1-7) and ACE2 in the uteroembryonic unit during early and late gestation ...
Angiotensin I-converting enzyme modulates neutral endopeptidase activity in the rat
(LIPPINCOTT WILLIAMS & WILKINS, 2001)
Angiotensin I is a substrate for both ACE and for neutral endopeptidase 24.11 (NEP). We hypothesized that high ACE expression is related to low NEP activity. Accordingly, circulating and tissue NEP and ACE activities were ...
Distribution of angiotensin-(1-7) and ACE2 in human placentas of normal and pathological pregnancies
(W B SAUNDERS CO LTD, 2006)
This work was designed to study the expression of the vasodilator peptide angiotensin-(1-7) [Ang-(1-7)] and its generating enzyme (ACE2) in the uteroplacental interface. Placentas were obtained from 11 early pregnancy ...