Microglial cells become dystrophic with aging; this phenotypic alteration contributes to basal central nervous system (CNS) neuroinflammation being a risk factor for age related neurodegenerative diseases. In previous ...

Dopamine neurotransmission has been consistently associated with individual differences in impulsive choice. Clinical and preclinical evidence suggests that low striatal dopamine D2 signaling predisposes to engage in ...

Bicuculline methiodide (BMI), a gamma-aminobutyrate (GABA) antagonist, is a powerful convulsant agent when injected into the cerebral ventricles, amygdala, hippocampus, thalamus, neocortex, and deep prepiriform cortex in ...

Little attention has been directed towards environmental control of sensitivity to natural reward and its possible relationship with other motivated behaviors, besides the well-known effects of environmental enrichment and ...

Little attention has been directed towards environmental control of sensitivity to natural reward and its possible relationship with other motivated behaviors, besides the well-known effects of environmental enrichment and ...