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Initiation and continuation of randomized trials after the publication of a trial stopped early for benefit asking the same study question: STOPIT-3 study design
(BioMed Central, 2013)
Background: Randomized control trials (RCTs) stopped early for benefit (truncated RCTs) are increasingly common and, on average, overestimate the relative magnitude of benefit by approximately 30%. Investigators stop trials ...
Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit
(Elsevier, 2017)
Objective: We explored how investigators of ongoing or planned trials respond to the publication of a trial stopped early for benefit addressing a similar question. Study Design and Setting: We searched multiple databases ...
Randomized controlled trials for COVID-19: evaluation of optimal randomization methodologies - need for the data validation of the completed trials, and to improve the ongoing and future randomized trial designs
COVID-19. The Recovery trials showed an Absolute Risk Reduction (ARR) in mortality by 2.8% with
Dexamethasone, and the ACTT-1 trial showed that the treatment with Remdesivir reduced the Time to
recovery by 4 days. The ...
Experimental Studies 1st Part. Clinical Trial [Estudios experimentales 1ª parte. El ensayo clínico]
(Universidad de la Frontera, 2015)
The Latin American ongoing clinical trial register (LATINREC)
(PAN AMER HEALTH ORGANIZATION, 2006)
Effects of physical activity governmental programs on health status in independent older adults: A systematic review
(Human Kinetics Publishers Inc., 2019)