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Polymorphisms in RAS/RAF/MEK/ERK pathway are associated with gastric cancer
(MDPI AG, 2019)
The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers ...
Raf/MEK/ERK pathway activation is required for Junín virus replication
(Society for General Microbiology, 2014)
Participación de las vías de señalización celular dependientes de proteínas quinasas activadas por mitógenos Raf/MEK/ERK y p38 en la multiplicación del virus JunínInvolvement of mitogen-activated protein kinase - dependent signaling pathways Raf/MEK/ERK and p38 in Junín virus multiplication
(2019-03-12)
El virus Junín (JUNV), miembro de la familia Arenaviridae, es el agente causal de la fiebre hemorrágica argentina, enfermedad endemo-epidémica que afecta una amplia zona central de la República Argentina y para la cual, ...
Polymorphisms in RAS/RAF/MEK/ERK Pathway Are Associated with Gastric Cancer
(2019)
The RAS/RAF/MEK/ERK pathway regulates certain cellular functions, including cell proliferation, differentiation, survival, and apoptosis. Dysregulation of this pathway leads to the occurrence and progression of cancers ...
Expression of scinderin in megakaryoblastic leukemia cells induces differentiation, maturation, and apoptosis with release of plateletlike particles and inhibits proliferation and tumorigenesis
(American Society of Hematology, 2001-10)
Rapid proliferation of atypical megakaryoblasts is a characteristic of megakaryoblastic leukemia. Cells from patients with this disorder and cell lines established from this type of leukemia showed the presence of gelsolin ...
Mecanismos moleculares involucrados en la señalización celular de la hormona CRH en el sistema nervioso centralMolecular mechanisms involved in CRH signaling in the central nervous system
(Facultad de Ciencias Exactas y Naturales. Universidad de Buenos Aires, 2013)
MageC2 protein is upregulated by oncogenic activation of MAPK pathway and causes impairment of the p53 transactivation function
(Elsevier Science, 2021-03)
Normal-to-tumor cell transition is accompanied by changes in gene expression and signal transduction that turns the balance toward cancer-cell phenotype, eluding by different mechanisms, the response of tumor-suppressor ...
The regulation of NHE₁ and NHE₃ activity by angiotensin II is mediated by the activation of the angiotensin II type I receptor/phospholipase C/calcium/calmodulin pathway in distal nephron cells
(Amsterdam, 2013-12-05)
Angiotensin II (Ang II), acting via the AT1 receptor, induces an increase in intracellular calcium [Ca(2+)]i that then interacts with calmodulin (CaM). The Ca(2+)/CaM complex directly or indirectly activates sodium hydrogen ...