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Alteraciones en el reclutamiento y activación de proteínas Rab durante la infección micobacterianaAlterations in recruitment and activation of Rab proteins during mycobacterial infection
(Instituto Nacional de SaludGrupo de Inmunología Celular e InmunogenéticaBogotá, Colombia, 2023)
Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis
(Oncotarget, 2015-09-08)
Metastatic oral squamous cell carcinoma (OSCC) is frequently associated with recurrent gene abnormalities at specific chromosomal loci. Here, we utilized array comparative genomic hybridization and genome-wide screening ...
Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis
(Oncotarget, 2016)
Hypoxia, a common condition of the tumor microenvironment, is associated with poor patient prognosis, tumor cell migration, invasion and metastasis. Recent evidence suggests that hypoxia alters endosome dynamics in tumor ...
Coxiella burnetii localizes in a Rab7-labeled compartment with autophagic characteristics
(Amer Soc Microbiology, 2002-10-01)
The obligate intracellular bacterium Coxiella burnetii, the agent of Q fever in humans and of coxiellosis in other animals, survives and replicates within large, acidified, phagolysosome-like vacuoles known to fuse homo- ...
Changes in Rab3D Expression and Distribution in the Acini of Sjogren's Syndrome Patients Are Associated With Loss of Cell Polarity and Secretory Dysfunction
(CIENCIAS, 2011)
OBJECTIVE: Oral and ocular dryness are frequent and serious symptoms of Sjögren's syndrome (SS) that reflect problems in secretion due to glandular dysfunction. Exocytosis, an important process in the secretory pathway, ...
Carpenter Syndrome: Extended RAB23 Mutation Spectrum and Analysis of Nonsense-mediated mRNA Decay
(WILEY-BLACKWELL, 2011)
Carpenter syndrome, a rare autosomal recessive disorder characterized by a combination of craniosynostosis, polysyndactyly, obesity, and other congenital malformations, is caused by mutations in RAB23, encoding a member ...