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Membrane-permeable Rab27A is a regulator of the acrosome reaction: Role of geranylgeranylation and guanine nucleotides
(Elsevier Science Inc, 2018-04)
The acrosome reaction is the regulated exocytosis of mammalian sperm's single secretory granule, essential for fertilization. It relies on small GTPases, the cAMP binding protein Epac, and the SNARE complex, among other ...
RAB27B requirement for stretch-induced exocytosis in bladder umbrella cells
(American Physiological Society, 2017-11-22)
Umbrella cells, which must maintain a tight barrier, modulate their apical surface area during bladder filling by exocytosis of an abundant, subapical pool of discoidal- and/or fusiform-shaped vesicles (DFVs). Despite the ...
Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth
(Society for Neuroscience, 2017)
Neurons communicate with each other through their axons and dendrites. However, a full characterization of the molecular mechanisms
involved in axon and dendrite formation is still incomplete. Neurite outgrowth requires ...
Rab35 functions in axon elongation are regulated by P53-related protein kinase in a mechanism that involves Rab35 protein degradation and the microtubule-associated protein 1B
(Society for Neuroscience, 2016)
© 2016 the authors. Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat ...
Cdk5 regulation of the grab-mediated rab8-rab11 cascade in axon outgrowth
(2017)
Neurons communicate with each other through their axons and dendrites. However, a full characterization of the molecular mechanisms involved in axon and dendrite formation is still incomplete. Neurite outgrowth requires ...
Small GTpases in acrosomal exocytosis
(Springer, 2015-01)
Regulated exocytosis employs a conserved molecular machinery in all secretory cells. Soluble N -ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Rab superfamilies are members of this machinery. Rab ...
Rab35 functions in axon elongation are regulated by PRPK in a mechanism that involves Rab35 protein degradation and MAP1B
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal
immortalized cells, Rab35 promotes neurite differentiation. Here we describe that
Rab35 favors axon elongation in rat primary neurons in an ...
Rab35 functions in axon elongation are regulated by p53-related protein kinase (prpk) in a mechanism that involves rab35 protein degradation and the microtubule-associated protein 1b
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat primary neurons in an ...
Rab35 functions in axon elongation are regulated by p53-related protein kinase in a mechanis that involves Rab35 protein degradation and the microtubule-associated protein 1B
(2016)
Rab35 is a key protein for cargo loading in the recycling endosome. In neuronal immortalized cells, Rab35 promotes neurite differentiation. Here we describe that Rab35 favors axon elongation in rat primary neurons in an ...