Buscar
Mostrando ítems 1-10 de 168
Small RAB GTPases Regulate Multiple Steps of Mitosis
(Frontiers, 2016-02)
GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the ...
Small GTPases as regulators of cell division
(Landes Bioscience, 2013-09)
The superfamily of small GTPases serves as a signal transducer to regulate a diverse array of cellular functions. The members of this superfamily are structurally and functionally classified into at least 5 groups (Ras, ...
Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation
(Wiley Blackwell Publishing, Inc, 2016-11)
Endocytosis is a multistep process engaged in extracellular molecules internalization. Several proteins including the Rab GTPases family coordinate the endocytic pathway. The small GTPase Rab7 is present in late endosome ...
Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation.
(Wiley, 2016)
Endocytosis is a multistep process engaged in extracellular molecules internalization. Several proteins including the Rab GTPases family coordinate the endocytic pathway. The small GTPase Rab7 is present in late endosome ...
Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation.
(Wiley, 2016)
Endocytosis is a multistep process engaged in extracellular molecules internalization. Several proteins including the Rab GTPases family coordinate the endocytic pathway. The small GTPase Rab7 is present in late endosome ...
Tuba activates cdc42 during neuronal polarization downstream of the small gtpase rab8a
(Society for Neuroscience, 2021-02)
The acquisition of neuronal polarity is a complex molecular process that depends on changes in cytoskeletal dynamics and directed membrane traffic, regulated by the Rho and Rab families of small GTPases, respectively. ...
Predominant Rab-GTPase amplicons contributing to oral squamous cell carcinoma progression to metastasis
(Oncotarget, 2015-09-08)
Metastatic oral squamous cell carcinoma (OSCC) is frequently associated with recurrent gene abnormalities at specific chromosomal loci. Here, we utilized array comparative genomic hybridization and genome-wide screening ...
RabGTPase-mediated trafficking: Its role in neurite formation
(Wiley Blackwell Publishing, Inc, 2014-03)
Neuronal cells are characterized by the presence of two confined domains, which are different in their cellular properties, biochemical functions and molecular identity. The generation of asymmetric domains in neurons ...
Rab GTPase signaling in neurite outgrowth and axon specification
(John Wiley and Sons Inc., 2016)
© 2016 Wiley Periodicals, Inc. Neurons are highly polarized cells that contain specialized subcellular domains involved in information transmission in the nervous system. Specifically, the somatodendritic compartment ...
Rab39a and Rab39b display different intracellular distribution and function in sphingolipids and phospholipids transport
(Molecular Diversity Preservation International, 2019-04)
Rab GTPases define the identity and destiny of vesicles. Some of these small GTPases present isoforms that are expressed differentially along developmental stages or in a tissue-specific manner, hence comparative analysis ...