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Morphological and molecular identification with frequency analysis of Calicophoron microbothrioides in central Chile
(Facultad de Medicina Veterinaria, 2019)
This research aimed to determine the presence of paramphistomids in cattle slaughtered in a slaughterhouse of the Ruble Region of Chile, to identify flukes and to analyze the frequency of these parasites in the Maule, ...
Albendazole enantiomeric metabolism and binding to cytosolic proteins in the liver fluke Fasciola hepatica
(Springer, 2008-08)
Fascioliasis causes important economic losses in ruminant species all over the world. Its control is largely based on the use of the flukicidal compound triclabendazole (TCBZ). However, its chemically related benzimidazole ...
Adaptive radiation of the flukes of the family fasciolidae inferred from genome-wide comparisons of key species
(Society for Molecular Biology and Evolution, 2020)
Liver and intestinal flukes of the family Fasciolidae cause zoonotic food–borne infections that impact both agriculture and human health throughout the world. Their evolutionary history and the genetic basis underlying ...
Eurytrema coelomaticum natural infection in small ruminants: a neglected condition
(Cambridge Univ Press, 2021-04-01)
Pancreatic eurytrematosis (PE) is an under diagnosed and neglected parasitosis in goats and sheep in the Americas. Clinical and pathological features of PE are not well defined in small ruminants worldwide. Natural cases ...
Characterization of a new albendazole resistant Fasciola hepatica isolate
(World Association for the Advancement of Veterinary Parasitology, 2021)
Characterization of a new albendazole resistant Fasciola hepatica isolateMaría Martínez-Valladares11,2, Elora Valderas-García1,2, Verónica Castilla Gómez de Agüero1,2, Marta González-Warleta3, Laura Ceballos4, Juan P. ...
Host pharmacokinetics and drug accumulation of anthelmintics within target helminth parasites of ruminants
(New Zealand Veterinary Assoc Inc, 2017-07)
Anthelmintic drugs require effective concentrations to be attained at the site of parasite location for a certain period to assure their efficacy. The processes of absorption, distribution, metabolism and excretion ...
Efficacy of oxyclozanide against adult Paramphistomum leydeni in naturally infected sheep
(Elsevier Science, 2014-10)
The aim of the current study was to assess oxyclozanide (OCZ) efficacy against Paramphistomum leydeni in naturally infected adult sheep. OCZ concentrations in blood stream and gastrointestinal fluids collected from treated ...
Understanding the main route of drug entry in adult Fasciola hepatica: Further insights into closantel pharmacological activity
(Academic Press Inc Elsevier Science, 2017-10)
Closantel (CLS) is highly effective against adult liver flukes after its oral or subcutaneous (sc) administration in ruminants. Trans-tegumental diffusion and oral ingestion are the two potential routes available for the ...
Histopathological findings of Fasciola hepatica infection in non-native European hare (Lepus europaeus) in Southern Chile
(Facultad de Medicina Veterinaria, 2019)
Fasciola hepatica is a parasite introduced in America from Europe, being considered of concern for public health and animal production, especially in countries with endemic areas as occur in Chile. In this country, the ...