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Respiratory Syncytial Virus Vaccines: A Review of the Candidates and the Approved Vaccines
(2023)
Respiratory syncytial virus (RSV) is responsible for a significant proportion of global morbidity and mortality affecting young children and older adults. In the aftermath of formalin-inactivated RSV vaccine development, ...
A safe and efficient BCG vectored vaccine to prevent the disease caused by the human Respiratory Syncytial Virus
(2017)
The human Respiratory Syncytial Virus (hRSV) causes lower respiratory tract infections including pneumonia and bronchiolitis. Such infections also cause a large number of hospitalizations and affects mainly newborns, young ...
Efficient Lung Recruitment of Respiratory Syncytial Virus-Specific Th1 Cells Induced by Recombinant Bacillus Calmette-Guerin Promotes Virus Clearance and Protects from Infection
(AMER ASSOC IMMUNOLOGISTS, 2010)
Infection by the respiratory syncytial virus (RSV) can cause extensive inflammation and lung damage in susceptible hosts due to a Th2-biased immune response. Such a deleterious inflammatory response can be enhanced by ...
Innate Immune Components That Regulate the Pathogenesis and Resolution of hRSV and hMPV Infections
(2020)
The human respiratory syncytial virus (hRSV) and human Metapneumovirus (hMPV) are two of the leading etiological agents of acute lower respiratory tract infections, which constitute the main cause of mortality in infants. ...
New Insights Contributing to the Development of Effective Vaccines and Therapies to Reduce the Pathology Caused by hRSV
(2017)
Human Respiratory Syncytial Virus (hRSV) is one of the major causes of acute lower respiratory tract infections (ALRTI) worldwide, leading to significant levels of immunocompromisation as well as morbidity and mortality ...
Antibody development for preventing the human respiratory syncytial virus pathology.
(2020)
Abstract
Human respiratory syncytial virus (hRSV) is the most important etiological agent causing hospitalizations associated with respiratory diseases in children under 5 years of age as well as the elderly, ...
Desired immune response characteristics in an RSV vaccine: What infants tell us
(Elsevier, 2009)
Respiratory syncytial virus (RSV) represents an important target for vaccine development. The design of an
effective vaccine for infants is hindered by a lack of knowledge of the nature of the protective immune response ...
Immunological Features of Respiratory Syncytial Virus-Caused Pneumonia-Implications for Vaccine Design.
(2017)
The human respiratory syncytial virus (hRSV) is the causative agent for high rates of hospitalizations due to viral bronchiolitis and pneumonia worldwide. Such a disease is characterized by an infection of epithelial cells ...
New Insights Contributing to the Development of Effective Vaccines and Therapies to Reduce the Pathology Caused by hRSV
(2017)
Human Respiratory Syncytial Virus (hRSV) is one of the major causes of acute lower respiratory tract infections (ALRTI) worldwide, leading to significant levels of immunocompromisation as well as morbidity and mortality ...
Human Respiratory Syncytial Virus: Infection and Pathology
(2016)
The human respiratory syncytial virus (hRSV) is by far the major cause of acute lower respiratory tract infections (ALRTIs) worldwide in infants and children younger than 2 years. The overwhelming number of hospitalizations ...