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RNA activation: A diamond in the rough for genome engineers
(Wiley-liss, Div John Wiley & Sons Inc, 2017-06)
The ability to develop efficient and versatile technologies for manipulating gene expression is a fundamental issue both in biotechnology and therapeutics. The endogenous RNA interference (RNAi) pathway which mediates gene ...
Cooperative RNA Polymerase Molecules Behavior on a Stochastic Sequence-Dependent Model for Transcription Elongation
(2013-02-21)
The transcription process is crucial to life and the enzyme RNA polymerase (RNAP) is the major component of the transcription machinery. The development of single-molecule techniques, such as magnetic and optical tweezers, ...
Beyond transcription: Fine-tuning of circadian timekeeping by post-transcriptional regulation
(MDPI, 2018-12)
The circadian clock is an important endogenous timekeeper, helping plants to prepare for the periodic changes of light and darkness in their environment. The clockwork of this molecular timer is made up of clock proteins ...
Competing endogenous RNA networks in the epithelial to mesenchymal transition in diffuse-type of gastric cancer
(MDPI, 2020)
The diffuse-type of gastric cancer is associated with epithelial to mesenchymal transition. Loss of E-cadherin expression is the hallmark of this process and is largely due to the upregulation of the transcription factors ...
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)
Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...
Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats
(2016-07-12)
Transcript variation has important implications for organismal function in health and disease. Most transcriptome studies focus on assessing variation in gene expression levels and isoform representation. Variation at the ...
Rrn7 protein, an rna polymerase i transcription factor, is required for rna polymerase ii-dependent transcription directed by core promoters with a homold box sequence
(AMERICAN SOCIETY FOR BIOCHEMISTRY AND MOLECULAR BIOLOGY, 2011)
The Trypanosoma brucei RNA-Binding protein TbRRM1 is involved in the transcription of a subset of RNA Pol II-Dependent genes
(Wiley Blackwell Publishing, Inc, 2019-09)
It has been long thought that RNA Polymerase (Pol) II transcriptional regulation does not operate in trypanosomes. However, recent reports have suggested that these organisms could regulate RNA Pol II transcription by ...
Influence of Leishmania RNA Virus-1 (LRV-1) on Virulence Factor RNA Transcript Expression of Leishmania Viannia spp
(Elsevier, 2018)
Background: Leishmania RNA Virus-1 (LRV-1) is a double stranded RNA virus identified in strains of the Viannia subgenus in Latin America. Virulence factors (VFs) are gene products that augment pathogenicity of an organism, ...