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Who Regulates Whom? An Overview of RNA Granules and Viral Infections
(MDPI AG, 2016)
After viral infection, host cells respond by mounting an anti-viral stress response in order to create a hostile atmosphere for viral replication, leading to the shut-off of mRNA translation (protein synthesis) and the ...
Translation and Silencing in RNA Granules: a Tale of Sand Grains
(Frontiers, 2014-07)
The transcriptome at the synapse consists of thousands of messengers encoding several cellular functions, including a significant number of receptors and ion channels and associated proteins. The concerted translational ...
HIV-2 genomic RNA accumulates in stress granules in the absence of active translation
(2014)
During the post-transcriptional events of the HIV-2
replication cycle, the full-length unspliced genomic
RNA (gRNA) is first used as an mRNA to synthesize
Gag and Gag-Pol proteins and then packaged into
progeny virions. ...
RNA-binding proteins related to stress response and differentiation in protozoa
(Jingfang Ju, 2016)
Trypanosoma cruzi XRNA granules colocalise with distinct mRNP granules at the nuclear periphery
(Fundação Oswaldo Cruz. Instituto Oswaldo Cruz, 2018)
Translation factor mRNA granules direct protein synthetic capacity to regions of polarized growth
(Rockefeller University Press, 2019-05)
mRNA localization serves key functions in localized protein production, making it critical that the translation machinery itself is present at these locations. Here we show that translation factor mRNAs are localized to ...
Rotavirus RNAs sponge host cell RNA binding proteins and interfere with their subcellular localization
(Academic Press Inc Elsevier Science, 2018-12)
Cellular mRNAs cycle between translating and non-translating pools, polysomes compose the translating pool, while RNA granules contain translationally-silenced mRNAs, where the RNAs are either stored in stress granules, ...
Synaptic control of mRNA translation by reversible assembly of XRN1 bodies
(Company of Biologists, 2015-04)
Repression of mRNA translation is linked to the formation of specific cytosolic foci such as stress granules and processing bodies, which store or degrade mRNAs. In neurons, synaptic activity regulates translation at the ...
Staufen Recruitment into Stress Granules Does Not Affect Early mRNA Transport in Oligodendrocytes
(American Society for Cell Biology, 2004-10)
Staufen is a conserved double-stranded RNA-binding protein required for mRNA localization in Drosophila oocytes and embryos. The mammalian homologues Staufen 1 and Staufen 2 have been implicated in dendritic RNA targeting ...
HIV-2 genomic RNA accumulates in stress granules in the absence of active translation
(2014)
© The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. During the post-transcriptional events of the HIV-2 replication cycle, the full-length unspliced genomic RNA (gRNA) is first ...