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Evolution of antitumor activity of 5 RNA interference in conjunction for the treatment of breast cancer in nude mice
(Fiocruz/Instituto de Tecnologia em Imunobiológicos, 2022)
RNA activation: A diamond in the rough for genome engineers
(Wiley-liss, Div John Wiley & Sons Inc, 2017-06)
The ability to develop efficient and versatile technologies for manipulating gene expression is a fundamental issue both in biotechnology and therapeutics. The endogenous RNA interference (RNAi) pathway which mediates gene ...
RNA interference against aldehyde dehydrogenase-2: development of tools for alcohol research
(2009)
Liver alcohol dehydrogenase oxidizes ethanol to acetaldehyde, which is further oxidized to acetate by aldehyde dehydrogenase-2 (ALDH2*1). Individuals who carry a low-activity ALDH2 (ALDH2*2) display high blood acetaldehyde ...
Avances y limitaciones en el uso de los dsRNA como estrategias de control y prevención de enfermedades virales en sistemas acuícolas
(Univ. Católica de Valparaíso, 2015)
El desarrollo de la acuicultura sustentable es acorde con la demanda creciente de nuevas metodologías que aseguren la salud de las diversas especies acuícolas. Dentro de ellas, el uso de terapias revolucionarias basadas ...