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Análise da função biológica da molécula orientadora por repulsão a1 (RGMA1) durante o estabelecimento de precursores musculares em somitos de embriões de galinha in vitro
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2018-02-28)
The Repulsive Guidance Molecule a (RGMa) is a protein originaly described playing
role as a repulsive cue during axonogenesis, via the Neogenin and/or as co-receptors of
the BMP signaling pathways. RGMa expression pattern ...
Avaliação das vias de sinalização induzidas pela molécula orientadora a (RGMa) solúvel durante a miogênese in vitro
(Universidade Federal de Minas GeraisBrasilICB - INSTITUTO DE CIÊNCIAS BIOLOGICASPrograma de Pós-Graduação em Biologia CelularUFMG, 2018-07-25)
RGMa is one of the members of the Repulsive Guidance Molecule (RGM) family, that were initialy found playing roles as clues to guide axon migration. Recent new studies have been pointing to a higher range of biological ...
Caracterização do perfil de expressão da molécula orientadora por repulsão a (RGMA) na musculatura esquelética atrofiada por denervação
(Universidade Federal de Minas GeraisUFMG, 2017-07-28)
Several physiological stimuli are capable of inducing modifications in the skeletal muscle, leading to an increase or loss of muscle mass. Many molecules are involved in both processes and recent studies have revealed the ...
Caracterização in situ dos orientadores de axônio por repulsão (RGMs) na musculatura esquelética, e caracterização funcional do membro A (RGMa) durante a miogênese em camundongos
(Universidade Federal de Minas GeraisUFMG, 2015-06-10)
Repulsive Guidance Molecules (RGMs) are negative cues that, during development, guide axonal growth in order to allow the proper innervation of the tissues and organs. RGMs compose a family of four members comprised by: ...
RGMa and RGMb expression pattern during chicken development suggest unexpected roles for these repulsive guidance molecules in notochord formation, somitogenesis, and myogenesis
(WILEY-BLACKWELLHOBOKEN, 2012)
Background: Repulsive guidance molecules (RGM) are high-affinity ligands for the Netrin receptor Neogenin, and they are crucial for nervous system development including neural tube closure; neuronal and neural crest cell ...
Deletion of the RMGA and CHD2 genes in a child with epilepsy and mental deficiency
(ELSEVIER SCIENCE BVAMSTERDAM, 2012)
We describe a novel chromosome microdeletion at 15q26.1 detected by oligo-array-CGH in a 6-year-old girl presenting with global development delay, epilepsy, autistic behavior and facial dysmorphisms. Although these features ...
Downregulation of the Sonic Hedgehog/Gli pathway transcriptional target Neogenin-1 is associated with basal cell carcinoma aggressiveness
(Impact Journals Llc., 2017)
Basal Cell Carcinoma (BCC) is one of the most diagnosed cancers worldwide. It develops due to an unrestrained Sonic Hedgehog (SHH) signaling activity in basal cells of the skin. Certain subtypes of BCC are more aggressive ...
Evaluación de neogenina-1 como gen blanco de la vía sonic hedgehog en carcinoma basocelular
(Universidad de Chile, 2015)
El Carcinoma Basocelular Cutáneo (BCC), un tipo de cáncer de piel, es una de las neoplasias más frecuentes en el ser humano. Es causado por una desregulación de la vía Sonic Hedgehog/Gli (Shh/Gli), cuya señalización juega ...
Netrina-4 anula la actividad proapoptótica del receptor de dependencia Neogenina 1, en un modelo de neuroblastoma humano
(Universisdad de Chile, 2014)
Neogenina 1,homologo del receptor "Deleted in Colorectal Cancer" (DCC), es un receptor transmembrana implicado en guiá axonal, aniogenesis, diferenciación neuronal, morfogenesis y muerte celular (apoptosis). Este receptor ...
Distribución del excedente económico : usos y patrón de desarrollo, Colombia 1990-2014
(Universidad Nacional de San Martín. Instituto de Altos Estudios Sociales, 2019)