Buscar
Mostrando ítems 1-10 de 1273
Histamine H2 overexpression induces U937 cell differentiation despite triggered mechanisms to attenuate cAMP signalling
(Elsevier, 2006-04)
Knowing that cell-surface receptors that recognize and respond to extracellular stimuli are key components for the regular communication between individual cells required for the survival of any living organism, the aim ...
Aryl hydrocarbon receptor overexpression in miniaturized follicles in female pattern hair loss
(2017-01-01)
The etiopathogenesis of female pattern hair loss is still poorly understood. In addition to genetic and hormonal elements, environmental factors could be involved. The aryl hydrocarbon receptor is expressed in keratinocytes ...
Overexpression of the pdz1 domain of pdzk1 blocks the activity of hepatic scavenger receptor, class b, type i by altering its abundance and cellular localization
(AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC, 2008)
The receptor-like kinase SlSOBIR1 is differentially modulated by virus infection but its overexpression in tobacco has no significant impact on virus accumulation
(Springer, 2015-09-25)
The role of the tomato receptor-like kinase SlSOBIR1 in antiviral defense was investigated. SlSOBIR1 was transcriptionally modulated by unrelated viruses but its ectopic expression had no effect on virus accumulation. ...
Effect of neoadjuvant chemotherapy on low-density lipoprotein (LDL) receptor and LDL receptor-related protein 1 (LRP-1) receptor in locally advanced breast cancer
(Associação Brasileira de Divulgação Científica, 2012)
Low-density lipoprotein (LDL) receptors are overexpressed in most neoplastic cell lines and provide a mechanism for the internalization and concentration of drug-laden nanoemulsions that bind to these receptors. The aim ...
GH modulates hepatic epidermal growth factor signaling in the mouse.
(BioScientifica, 2010-03)
Epidermal growth factor (EGF) is a key regulator of cell survival and proliferation involved in the pathogenesis and progression of different types of cancer. The EGF receptor (EGFR) is activated by binding of the specific ...
Muscle-specific growth hormone receptor (GHR) overexpression induces hyperplasia but not hypertrophy in transgenic zebrafish
(Springer, 2012-06-01)
Even though growth hormone (GH) transgenesis has demonstrated potential for improved growth of commercially important species, the hormone excess may result in undesired collateral effects. In this context, the aim of this ...