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Corneal stroma PDGF blockade and myofibroblast development
(ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, 2009)
Myofibroblast development and haze generation in the corneal stroma is mediated by cytokines, including transforming growth factor-beta (TGF-beta), and possibly other cytokines. This study examined the effects of stromal ...
Immunohistochemical analysis of pdgfr-alpha, pdgfr-beta and c-abl in retinoblastoma: potential therapeutic targets
(Karger, 2016)
Background: Our laboratory previously reported that imatinib mesylate (IM) has an inhibitory effect on two retinoblastoma (Rb) cell lines in vitro. Aims: The purpose of this project was to determine the immunoexpression ...
Transforming Growth Factor Beta (TGFβ1) and Epidermal Growth Factor (EGF) as Biomarkers of Leishmania (V) braziliensis Infection and Early Therapeutic Response in Cutaneous Leishmaniasis: Studies in Hamsters
(Frontiers MediaPrograma de Estudio y Control de Enfermedades Tropicales (PECET)Lausana, Suiza, 2023)
Mechanisms of liver fibrosis associated with experimental fasciola hepatica infection: Roles of Fas2 proteinase and hepatic stellate cell activation
(American Society of Parasitologists, 2011)
We have evaluated the possible mechanisms of liver fibrosis caused by Fasciola hepatica in an animal model and in culture using immortalized human stellate cells. Liver biopsies of F. hepatica-infected rats were performed ...
Endothelial PPARγ Is Crucial for Averting Age-Related Vascular Dysfunction by Stalling Oxidative Stress and ROCK
(Springer New York LLC, 2019)
Comparison of two experimental models of pulmonary hypertension
(SOCIEDADE BRASILEIRA PNEUMOLOGIA TISIOLOGIABRASILIA, 2012)
Objective: To compare two models of pulmonary hypertension (monocrotaline and monocrotaline+pneumonectomy) regarding hemodynamic severity, structure of pulmonary arteries, inflammatory markers (IL-1 and PDGF), and 45-day ...
Effects of two platelet-rich gel supernatants at two concentrations on healthy cartilage explants from horses
(Faculty of Veterinary Sciences - Universidad Austral de Chile, 2017)
TGFβ activity released from platelet-rich fibrin adsorbs to titanium surface and collagen membranes
(Nature, 2020)
Platelet-rich fibrin (PRF) contains a broad spectrum of bioactive molecules that can trigger several cellular responses. However, these molecules along with their upstream responses remain mostly uninvestigated. By means ...
ALS skeletal muscle shows enhanced TGF-beta signaling, fibrosis and induction of fibro/adipogenic progenitor markers
(2017)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease in which upper and lower motoneurons degenerate leading to muscle wasting, paralysis and eventually death from respiratory failure. Several studies ...