Buscar
Mostrando ítems 1-10 de 130
The proinflammatory RAGE/NF-κB pathway is involved in neuronal damage and reactive gliosis in a model of sleep apnea by intermittent hypoxia
(Public Library of Science, 2014-09)
Sleep apnea (SA) causes long-lasting changes in neuronal circuitry, which persist even in patients successfully treated for the acute effects of the disease. Evidence obtained from the intermittent hypoxia (IH) experimental ...
Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes
(Frontiers, 2016-06)
Reactive gliosis involving activation and proliferation of astrocytes and microglia, is a widespread but largely complex and graded glial response to brain injury. Astroglial population has a previously underestimated high ...
Predicting Reactive Astrogliosis Propagation by Bayesian Computational Modeling: the Repeater Stations Model
(Humana Press, 2019-09)
Reactive astrogliosis occurs upon focal brain injury and in neurodegenerative diseases. The mechanisms that propagate reactive astrogliosis to distal parts of the brain, in a rapid wave that activates astrocytes and other ...
S100B protein activates a RAGE-dependent autocrine loop in astrocytes: implications for its role in the propagation of reactive gliosis
(Wiley, 2014-06)
Extracellular S100B dramatically increases after brain injury. While low S100B levels are neuroprotective, micromolar S100B levels have shown in vitro to activate microglia and facilitate neuronal death. In astrocytes, ...
Metabolic and Inflammatory Adaptation of Reactive Astrocytes: Role of PPARs
(Humana Press Inc., 2017)
Gabapentin Administration Reduces Reactive Gliosis and Neurodegeneration after Pilocarpine-Induced Status Epilepticus
(Public Library Science, 2013-11-08)
The lithium-pilocarpine model of epilepsy reproduces in rodents several features of human temporal lobe epilepsy, by inducing an acute status epilepticus (SE) followed by a latency period. It has been proposed that the ...
Progesterone attenuates astro and microgliosis and enhances oligodendrocyte differentittion following spinal cord injury
(Elsevier Inc, 2011-09)
Reactive gliosis, demyelination and proliferation of NG2+ oligodendrocyte precursor cells (OPC) are common responses to spinal cord injury (SCI). We previously reported that short-term progesterone treatment stimulates OPC ...
Prednisone induces cognitive dysfunction, neuronal degeneration, and reactive gliosis in rats
(LIPPINCOTT WILLIAMS & WILKINS, 2002)
Prednisone induces cognitive dysfunction, neuronal degeneration, and reactive gliosis in rats
(LIPPINCOTT WILLIAMS & WILKINS, 2002)