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Grab recruitment by Rab27A-Rabphilin3a triggers Rab3A activation in human sperm exocytosis
(Elsevier Science, 2019-04)
Sperm must undergo the regulated exocytosis of its dense core granule (the acrosome reaction, AR) to fertilize the egg. We have previously described that Rabs3 and 27 are organized in a RabGEF cascade within the signaling ...
Small GTpases in acrosomal exocytosis
(Springer, 2015-01)
Regulated exocytosis employs a conserved molecular machinery in all secretory cells. Soluble N -ethylmaleimide-sensitive factor attachment protein receptor (SNARE) and Rab superfamilies are members of this machinery. Rab ...