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R-spondin3 Is Associated with Basal-Progenitor Behavior in Normal and Tumor Mammary Cells

Tocci, Johanna M.; Felcher, Carla M.; García Solá, Martín E.; Goddio, María Victoria; Zimberlin, María Noel; Rubinstein, Natalia; Srebrow, Anabella; Coso, Omar A.; Abba, Martín Carlos; Meiss, Roberto P.; Kordon, Edith C. (2018)

R-Spondin3 is associated with basal-progenitor behavior in normal and tumor mammary cells

Tocci, Johanna Melisa; Felcher, Carla María; Garcia Sola, Martin Emilio; Goddio, Maria Victoria; Zimberlin, Maria Noel; Rubinstein, Natalia; Srebrow, Anabella; Coso, Omar Adrian; Abba, Martín Carlos; Meissl, Roberto Jose; Kordon, Edith Claudia (American Association for Cancer Research, 2018-08)

R-spondin3 (RSPO3) is a member of a family of secreted proteins that enhance Wnt signaling pathways in diverse processes, including cancer. However, the role of RSPO3 in mammary gland and breast cancer development remains ...

No mutation in genes of the WNT signaling pathway in patients with Zimmermann-Laband syndrome

Abo-Dalo, B; Roes, M; Canun, S; Delatycki, M; Gillessen-Kaesbach, G; Hrytsiuk, I; Jung, C; Kerr, B; Mowat, D; Seemanova, E; Steiner, CE; Stewart, H; Thierry, P; van Buggenhout, G; White, S; Zenker, M; Kutsche, K (Lippincott Williams & WilkinsPhiladelphiaEUA, 2008)

R-spondin-mediated WNT signaling potentiation in mammary and breast cancer development

Tocci, Johanna Melisa; Felcher, Carla María; Garcia Sola, Martin Emilio; Kordon, Edith Claudia (John Wiley & Sons Inc, 2020-08)

The mammary gland is a secretory organ, which develops as a network of growing epithelial ducts composed of luminal and basal cells that invade the surrounding adipose tissue through a series of developmental cycles. Mammary ...

RUNX1 and FOXP3 interplay regulates expression of breast cancer related genes

Recouvreux, Sol; Grasso, Esteban Nicolas; Echeverria, Pablo Christian; Rocha Viegas, Luciana; Castilla, Lucio Hernán; Schere Levy, Carolina Paula; Tocci, Johanna Melisa; Kordon, Edith Claudia; Rubinstein, Natalia (Impact Journals, 2015-12)

Abstract Runx1 participation in epithelial mammary cells is still under review. Emerging data indicates that Runx1 could be relevant for breast tumor promotion. However, to date no studies have specifically evaluated the ...