Buscar
Mostrando ítems 1-10 de 91
Four-Dimensional Structure-Activity Relationship Model to Predict HIV-1 Integrase Strand Transfer Inhibition using LQTA-QSAR Methodology
(Amer Chemical SocWashingtonEUA, 2012)
QSAR applications during last decade on inhibitors of acetylcholinesterase in Alzheimer's disease
(Bentham Science Publishers, 2012-05)
This article reviews multi-criteria QSAR applications on Acetylcholinesterase inhibitors as palliative drugs for Alzheimer's Disease, published in the period 2001-2011. It includes QSAR models for different series of ...
QSAR Applications on Polycyclic Aromatic Hydrocarbons and some derivatives
(Bentham Science Publishers, 2013-12)
Polycyclic Aromatic Hydrocarbons (PAHs) have been the focus of great attention for a long time owing to their impact on public health and the environment. In this article we overview various QSAR studies on PAHs and some ...
QSAR on aryl-piperazine derivatives with activity on malaria
(Elsevier Science, 2012-01-15)
In this work we offer linear regression models on a set of aryl-piperazine derivatives that are obtained by exploring a pool containing 1497 Dragon molecular descriptors, in order to establish the best relationships linking ...
Advances in the Replacement and Enhanced Replacement Method in QSAR and QSPR Theories
(American Chemical Society, 2011-04)
The selection of an optimal set of molecular descriptors from a much greater pool of such regression variables is a crucial step in the development of QSAR and QSPR models. The aim of this work is to further improve this ...
Anticonvulsant activity of ringed enaminones: a QSAR study
(Wiley VCH Verlag, 2009-12)
The formalism of the QSAR Theory is employed to establish mathematical relationships that link the molecular structure of ringed enaminones to their observed antiepileptic activity. The design of predictive linear regression ...
The Importance of the QSAR-QSPR Methodology to the Theoretical Study of Pesticides
(Nova Science Publishers, 2013-04)
In this paper, we reviewed various interesting applications of the Quantitative Structure-Activity/Property Relationships (QSAR-QSPR) Theory in pesticide research, with special emphasis on studies developed during the last ...