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Bioactive pyrrole-based compounds with target selectivity
The discovery of novel synthetic compounds with drug-like properties is an ongoing challenge in
medicinal chemistry. Natural products have inspired the synthesis of compounds for pharmaceutical
application, most of which ...
Síntese de 3-Trifluoracetil-1H-pirróis N-Aril substituídos
(Universidade Federal de Santa MariaBRQuímicaUFSMPrograma de Pós-Graduação em Química, 2011-07-29)
This work presents a new, simple and versatile strategy for the synthesis of new N-aryl substituted 3-trifluoroacetyl-1H-pyrroles. The pyrroles were obtained by the reaction of 3-trifluoroacetyl-4,5-dihydrofuran with aryl ...
An ultrasensitive human cardiac troponin T graphene screen-printed electrode based on electropolymerized-molecularly imprinted conducting polymer
(2016-03-15)
A nano-molecularly imprinted polymer (N-MIP) assembled on a screen-printed electrode for the cardiac troponin T (cTnT) was developed. The biomimetic surface was obtained by a co-polymer matrix assembled on the reduced ...
Green Synthesis of Pyrrole Derivatives
(Bentham Science Publishers, 2017-01)
Background: Pyrroles are organic cyclic compounds with an extensive and fascinating chemistry. These compounds have a wide structural variety and they are an important basis in technological development as they can be used ...
Synthesis and Antifungal Activity of 4‐ and 6‐(1 H ‐Pyrrol‐1‐yl) Coumarins, and their Thiocyanato Derivatives
(Wiley, 2019-05)
Facile and efficient syntheses of 4‐(1H ‐pyrrol‐1‐yl)‐coumarins and 6‐(1H ‐pyrrol‐1‐yl)‐coumarins from the corresponding aminocoumarins are reported. The transformations were optimized and their corresponding scope and ...
Síntese de novos pirróis derivados de aminocumarinas
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2018-07-19)
In this work, the synthesis of new pyrroles derived from aminocoumarins was
developed. First, the synthesis of pyrroles derived from 4-amino-2H-chromen-2-one
was carried out by the Paal-Knorr and Clauson-Kaas reactions, ...
Síntese de 1-alquil-4-aminoalquil-2-trifluormetil-1H-pirróis e 1,2,3- triazóis derivados
(Universidade Federal de Santa MariaBrasilQuímicaUFSMPrograma de Pós-Graduação em QuímicaCentro de Ciências Naturais e Exatas, 2020-12-04)
In the present work, it was carried out a study of the reactivity of 5-bromo-1,1,1-trifluoro-
4-methoxypent-3-en-2-one (5-bromo enone) towards primary aliphatic amines, which furnishes
as products two novel series of ...
Novel bifunctional mesoporous catalysts based on preyssler heteropolyacids for green pyrrole derivative synthesis
(Molecular Diversity Preservation International, 2018-10-26)
In this paper, we report the synthesis of Preyssler heteropolyacids supported on mesoporous alumina in order to obtain materials with acid–base properties. A series of pyrrole derivatives were synthesized using a suitable ...
Synthesis of Chromeno[4,3-b]pyrrol-4(1H)-ones, from β-Nitroalkenes and 4-Phenylaminocoumarins, under Solvent–free Conditions
(Wiley Blackwell Publishing, Inc, 2017-01)
A new approach toward chromeno[4,3-b]pyrrol-4(1H)-ones, by annulation of 4-phenylaminocoumarins with β-nitroalkenes, is reported and its conditions were optimized. The transformations under the fine-tuned conditions took ...